Postgraduate Program in Health and Nutrition, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil.
Physical Education School, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil.
Biomed Res Int. 2020 Sep 4;2020:7351716. doi: 10.1155/2020/7351716. eCollection 2020.
Aging is a biological process during which chronic low-grade inflammation is present due to changes in the immune system of the elderly. The main objective of this study is to evaluate the effects of resistance training associated with dietary advice on chronic inflammation in the elderly. We conducted a prospective intervention study in which we evaluated anthropometric parameters and inflammatory biomarkers (CRP, IL-8, CCL-2, and leptin) in 40 elderly people before and after long-term progressive resistance training (19 weeks) associated with dietary advice. The participants trained twice a week on nonconsecutive days, and the training lasted one hour with an intensity of 60-85% of 1-MR. Dietary advice was explained in person and individually focusing on foods rich in compounds with anti-inflammatory and antioxidant properties. Participants were instructed at the beginning of the training program, and dietary advice was reinforced verbally weekly. There was an improvement in body composition evidenced by a reduction in waist circumference and body fat percentage and by the increase in arm circumference, calf circumference, and corrected arm muscle area. In addition, there was a reduction in the inflammatory biomarkers CCL-2 ( = 0.01) and leptin ( < 0.01). Resistance training associated with dietary guidance can contribute to a healthy aging due to observed improvements in body composition and in the inflammatory profile of the elderly.
衰老是一个生物学过程，由于老年人免疫系统的变化，慢性低度炎症持续存在。本研究的主要目的是评估抗阻训练联合饮食建议对老年人慢性炎症的影响。我们进行了一项前瞻性干预研究，在该研究中，我们在长期渐进式抗阻训练（19 周）之前和之后评估了 40 名老年人的人体测量参数和炎症生物标志物（CRP、IL-8、CCL-2 和瘦素），并伴有饮食建议。参与者每周非连续两天训练两次，每次训练持续一小时，强度为 1-MR 的 60-85%。饮食建议是亲自解释的，并侧重于富含具有抗炎和抗氧化特性的化合物的食物。在训练计划开始时，参与者就接受了指导，并每周进行口头强化饮食建议。身体成分得到了改善，腰围和体脂百分比减少，手臂围度、小腿围度和校正手臂肌肉面积增加。此外，炎症生物标志物 CCL-2（ = 0.01）和瘦素（ < 0.01）减少。抗阻训练联合饮食指导有助于健康衰老，因为观察到老年人的身体成分和炎症特征得到了改善。
