Neuromuscular Research Center, Biology of Physical Activity, Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.
Department of Molecular and Cellular Sport Medicine, German Sport University Cologne, Cologne, Germany.
Scand J Med Sci Sports. 2018 Jan;28(1):40-47. doi: 10.1111/sms.12906. Epub 2017 Jun 13.
Our primary aim was to study the effects of 24 weeks of combined aerobic and resistance training performed on the same day or on different days on inflammation markers. Physically active, healthy young men were randomly divided into three groups that performed: aerobic and resistance training consecutively in the same training session (SS) 2-3 days wk or on alternating days (AD) 4-6 days wk as well as control (C). The total training volume was matched in the training groups. The control group was asked to maintain their habitual physical activity and exercise level. Maximal leg press strength (1RM) and peak oxygen uptake (VO2 ) were measured. Abdominal fat mass was estimated with dual-energy absorptiometry (DXA). High-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), monocyte chemoattractant protein 1 (MCP-1), tumor necrosis factor alpha (TNF-α), and adipocytokines resistin, adiponectin, and leptin were analyzed from plasma samples. Training significantly reduced circulating hs-CRP, leptin, and resistin in both training groups (P<.05), whereas MCP-1 and TNF-α decreased only in AD (P<.05). Significant correlations were observed between changes in abdominal fat mass and corresponding changes in MCP-1, leptin, adiponectin, and resistin. Long-term combined aerobic and resistance training reduced markers of subclinical inflammation in healthy young men. The results indicate that a higher frequency of individual exercise sessions might be more beneficial with respect to the anti-inflammatory effects of physical activity. The decreases in inflammation markers seem to be related to decreases in abdominal fat mass.
我们的主要目的是研究在同一天或不同天进行 24 周的有氧和阻力训练对炎症标志物的影响。身体活跃、健康的年轻男性被随机分为三组，分别进行：连续在同一训练课中进行有氧和阻力训练（SS）2-3 天/周或交替进行（AD）4-6 天/周，以及对照组（C）。训练组的总训练量相匹配。要求对照组保持其习惯性的身体活动和运动水平。测量最大腿部按压强度（1RM）和峰值摄氧量（VO2）。使用双能吸收仪（DXA）估计腹部脂肪量。分析来自血浆样本的高敏 C 反应蛋白（hs-CRP）、白细胞介素 6（IL-6）、单核细胞趋化蛋白 1（MCP-1）、肿瘤坏死因子-α（TNF-α）以及脂肪细胞因子抵抗素、脂联素和瘦素。训练显著降低了两组训练者的循环 hs-CRP、瘦素和抵抗素（P<.05），而 MCP-1 和 TNF-α仅在 AD 组中降低（P<.05）。观察到腹部脂肪量的变化与 MCP-1、瘦素、脂联素和抵抗素的相应变化之间存在显著相关性。长期的有氧和阻力训练联合降低了健康年轻男性亚临床炎症的标志物。结果表明，更高频率的个体运动课程可能更有益于身体活动的抗炎作用。炎症标志物的减少似乎与腹部脂肪量的减少有关。
