Institute of Bacterial Infections and Zoonoses (IBIZ), Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 07743 Jena, Germany.
Genes (Basel). 2020 Sep 21;11(9):1104. doi: 10.3390/genes11091104.
is the most prevalent species and has been isolated from a wide variety of sources. This species is an emerging foodborne and zoonotic pathogen because the bacteria can be transmitted by contaminated food or water and can cause acute enteritis in humans. Currently, there is no database to identify antimicrobial/heavy metal resistance and virulence-associated genes specific for . The aim of this study was to investigate the antimicrobial susceptibility and resistance profile of two isolates from Muscovy ducks () reared on a water poultry farm in Thuringia, Germany, and to create a database to fill this capability gap. The taxonomic classification revealed that the isolates belong to the gen. nov. as comb. nov. The antibiotic susceptibility was determined using the gradient strip method. While one of the isolates was resistant to five antibiotics, the other isolate was resistant to only two antibiotics. The presence of antimicrobial/heavy metal resistance genes and virulence determinants was determined using two custom-made databases. The custom-made databases identified a large repertoire of potential resistance and virulence-associated genes. This study provides the first resistance and virulence determinants database for .
是最普遍的 物种，已从多种来源中分离出来。该物种是一种新兴的食源性病原体和人畜共患病原体，因为细菌可以通过污染的食物或水传播，并可能导致人类急性肠炎。目前，尚无数据库可识别特定于 的抗微生物/重金属耐药性和毒力相关基因。本研究旨在调查德国图林根州水上家禽养殖场饲养的麝香鸭（）中分离出的两种 分离株的抗微生物敏感性和耐药谱，并创建一个数据库来填补这一能力差距。分类学分类表明，这些分离株属于 属。新型组合。使用梯度条带法测定抗生素敏感性。其中一个分离株对五种抗生素有耐药性，而另一个分离株仅对两种抗生素有耐药性。使用两个定制数据库确定了抗微生物/重金属耐药基因和毒力决定因素的存在。定制数据库确定了大量潜在的耐药性和毒力相关基因。本研究为 提供了第一个耐药性和毒力决定因素数据库。
