Department of Preventive Medicine, School of Health Sciences, Wuhan University, Wuhan 430071, China.
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
Int J Environ Res Public Health. 2021 Apr 1;18(7):3680. doi: 10.3390/ijerph18073680.
The goal of this study was to investigate the associations of midday nap duration and change in midday nap duration with hypertension in a retrospective cohort using a nationwide representative sample of middle-aged and older Chinese adults. Data were obtained from the China Health and Retirement Longitudinal Study (CHARLS) database during 2011-2015. Information on midday nap duration was collected via a self-reported questionnaire and blood pressure was objectively measured. Hazard ratios (HR) with 95% confidence interval (CI) were estimated using Cox proportional hazards regression models to quantify the associations. A sample of 5729 Chinese adults (≥45 years old) were included in the longitudinal analysis. Relative to non-nappers, participants who napping for ≥90 min/day was associated with significantly larger HR for hypertension at four-year follow-up (HR = 1.18, 95% CI = 1.01-1.40, = 0.048). Compared with people who napped ≥90 min/day both at baseline (2011) and follow-up (2013), hypertension risk at four-year follow-up declined in individuals whose midday nap durations decreased in the 2-year study period from ≥ 90 min/day to 1-59 min/day (HR = 0.59, 95% CI = 0.36-0.97, = 0.037) and 60-89 min/day (HR = 0.68, 95% CI = 0.47-0.99, = 0.044). Among middle-aged and older Chinese adults, relative to non-nappers, people who had longer midday nap duration (≥90 min/day) were associated with significantly larger HR for hypertension and decreased napping duration may confer benefit for hypertension prevention.
本研究旨在使用全国代表性的中老年中国人群队列，通过回顾性研究，调查午睡时长及其变化与高血压之间的关联。研究数据来自于 2011 年至 2015 年的中国健康与养老追踪调查（CHARLS）数据库。通过自报问卷收集午睡时长信息，采用客观血压测量法。使用 Cox 比例风险回归模型估计风险比（HR）及其 95%置信区间（CI），以量化两者的关联。共有 5729 名中国成年人（≥45 岁）纳入纵向分析。与非午睡者相比，每天午睡≥90 分钟的参与者在四年随访时发生高血压的 HR 显著更大（HR=1.18，95%CI=1.01-1.40， =0.048）。与基线（2011 年）和随访（2013 年）时每天午睡≥90 分钟的人相比，午睡时长在 2 年研究期间从≥90 分钟/天减少至 1-59 分钟/天（HR=0.59，95%CI=0.36-0.97， =0.037）和 60-89 分钟/天（HR=0.68，95%CI=0.47-0.99， =0.044）的个体，其四年随访时发生高血压的风险降低。在中老年中国成年人中，与非午睡者相比，午睡时间较长（≥90 分钟/天）与高血压的 HR 显著更大相关，而减少午睡时长可能有益于预防高血压。
