Androgen receptor genetic variant predicts COVID-19 disease severity: a prospective longitudinal study of hospitalized COVID-19 male patients.
作者信息
McCoy J, Wambier C G, Herrera S, Vaño-Galván S, Gioia F, Comeche B, Ron R, Serrano-Villar S, Iwasiow R M, Tayeb M A, Cadegiani F A, Mesinkovska N A, Shapiro J, Sinclair R, Goren A
机构信息
Applied Biology, Inc., Irvine, CA, USA.
Department of Dermatology, Alpert Medical School of Brown University, Providence, RI, USA.
出版信息
J Eur Acad Dermatol Venereol. 2021 Jan;35(1):e15-e17. doi: 10.1111/jdv.16956. Epub 2020 Oct 21.
Abstract
摘要
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Sex hormones signal why virus hits men harder.性激素揭示病毒为何对男性影响更大。
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Androgenetic alopecia present in the majority of patients hospitalized with COVID-19: The "Gabrin sign".雄激素性脱发在大多数因新冠肺炎住院的患者中出现：“加布林征” 。
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Androgen-deprivation therapies for prostate cancer and risk of infection by SARS-CoV-2: a population-based study (N = 4532).雄激素剥夺疗法治疗前列腺癌与 SARS-CoV-2 感染风险的关系：一项基于人群的研究（N=4532）。
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Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy.蛋白质精氨酸甲基转移酶6增强脊髓延髓性肌萎缩症中多聚谷氨酰胺扩展的雄激素受体功能及毒性。
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