大肠杆菌用于需氧利用L-岩藻糖和L-鼠李糖的NAD连接醛脱氢酶。
NAD-linked aldehyde dehydrogenase for aerobic utilization of L-fucose and L-rhamnose by Escherichia coli.
作者信息
Chen Y M, Zhu Y, Lin E C
出版信息
J Bacteriol. 1987 Jul;169(7):3289-94. doi: 10.1128/jb.169.7.3289-3294.1987.
Abstract
Mutant analysis revealed that complete utilization of L-fucose and L-rhamnose by Escherichia coli requires the activity of a common NAD-linked aldehyde dehydrogenase which converts L-lactaldehyde to L-lactate. Mutations affecting this activity mapped to the ald locus at min 31, well apart from the fuc genes (min 60) encoding the trunk pathway for L-fucose dissimilation (as well as L-1,2-propanediol oxidoreductase) and the rha genes (min 88) encoding the trunk pathway for L-rhamnose dissimilation. Mutants that grow on L-1,2-propanediol as a carbon and energy source also depend on the ald gene product for the conversion of L-lactaldehyde to L-lactate.
摘要
突变分析表明，大肠杆菌对L-岩藻糖和L-鼠李糖的完全利用需要一种常见的NAD连接的醛脱氢酶的活性，该酶将L-乳醛转化为L-乳酸。影响该活性的突变定位于31分钟处的ald位点，与编码L-岩藻糖异化主干途径（以及L-1,2-丙二醇氧化还原酶）的fuc基因（60分钟处）和编码L-鼠李糖异化主干途径的rha基因（88分钟处）相距甚远。以L-1,2-丙二醇作为碳源和能源生长的突变体也依赖ald基因产物将L-乳醛转化为L-乳酸。
相似文献
1
NAD-linked aldehyde dehydrogenase for aerobic utilization of L-fucose and L-rhamnose by Escherichia coli.大肠杆菌用于需氧利用L-岩藻糖和L-鼠李糖的NAD连接醛脱氢酶。
J Bacteriol. 1987 Jul;169(7):3289-94. doi: 10.1128/jb.169.7.3289-3294.1987.
2
Metabolism of L-fucose and L-rhamnose in Escherichia coli: aerobic-anaerobic regulation of L-lactaldehyde dissimilation.大肠杆菌中L-岩藻糖和L-鼠李糖的代谢：L-乳醛异化作用的好氧-厌氧调节
J Bacteriol. 1988 Jan;170(1):416-21. doi: 10.1128/jb.170.1.416-421.1988.
3
Cross-induction of the L-fucose system by L-rhamnose in Escherichia coli.鼠李糖对大肠杆菌中L-岩藻糖系统的交叉诱导作用。
J Bacteriol. 1987 Aug;169(8):3712-9. doi: 10.1128/jb.169.8.3712-3719.1987.
4
Loss of aldehyde dehydrogenase in an Escherichia coli mutant selected for growth on the rare sugar L-galactose.在为在稀有糖L-半乳糖上生长而筛选出的大肠杆菌突变体中醛脱氢酶的缺失。
J Bacteriol. 1987 Feb;169(2):785-9. doi: 10.1128/jb.169.2.785-789.1987.
5
Dual control of a common L-1,2-propanediol oxidoreductase by L-fucose and L-rhamnose in Escherichia coli.大肠杆菌中L-岩藻糖和L-鼠李糖对一种常见的L-1,2-丙二醇氧化还原酶的双重调控
J Bacteriol. 1984 Mar;157(3):828-32. doi: 10.1128/jb.157.3.828-832.1984.
6
Genetic and structural evidence for the presence of propanediol oxidoreductase isoenzymes in Escherichia coli.大肠杆菌中存在1,2-丙二醇氧化还原酶同工酶的遗传和结构证据。
J Gen Microbiol. 1984 Mar;130(3):687-92. doi: 10.1099/00221287-130-3-687.
7
Functional Analysis of Deoxyhexose Sugar Utilization in Escherichia coli Reveals Fermentative Metabolism under Aerobic Conditions.大肠杆菌中脱氧己糖利用的功能分析揭示了有氧条件下的发酵代谢。
Appl Environ Microbiol. 2021 Jul 27;87(16):e0071921. doi: 10.1128/AEM.00719-21.
8
Disruption of the fucose pathway as a consequence of genetic adaptation to propanediol as a carbon source in Escherichia coli.由于大肠杆菌对丙二醇作为碳源的遗传适应，岩藻糖途径受到破坏。
J Bacteriol. 1976 Jun;126(3):1166-72. doi: 10.1128/jb.126.3.1166-1172.1976.
9
Metabolism of L-fucose and L-rhamnose in Escherichia coli: differences in induction of propanediol oxidoreductase.大肠杆菌中L-岩藻糖和L-鼠李糖的代谢：1,2-丙二醇氧化还原酶诱导的差异
J Bacteriol. 1981 Jul;147(1):181-5. doi: 10.1128/jb.147.1.181-185.1981.
10
Evolution of L-1, 2-propanediol catabolism in Escherichia coli by recruitment of enzymes for L-fucose and L-lactate metabolism.通过招募参与L-岩藻糖和L-乳酸代谢的酶，大肠杆菌中L-1,2-丙二醇分解代谢的进化。
J Bacteriol. 1974 Apr;118(1):83-8. doi: 10.1128/jb.118.1.83-88.1974.
引用本文的文献
1
NAD-dependent dehydrogenases enable efficient growth of Paracoccus denitrificans on the PET monomer ethylene glycol.烟酰胺腺嘌呤二核苷酸（NAD）依赖性脱氢酶使反硝化副球菌能够在聚对苯二甲酸乙二酯（PET）单体乙二醇上高效生长。
Nat Commun. 2025 Jul 1;16(1):5845. doi: 10.1038/s41467-025-61056-x.
2
Human xenobiotic metabolism proteins have full-length and split homologs in the gut microbiome.人类异源生物代谢蛋白在肠道微生物群中存在全长和分裂的同源物。
bioRxiv. 2024 Nov 8:2024.11.06.622278. doi: 10.1101/2024.11.06.622278.
3
Pathogenomic analysis and characterization of strains recovered from human infections.从人类感染中分离出的 株的病原基因组分析和特征描述。
Microbiol Spectr. 2024 Apr 2;12(4):e0380523. doi: 10.1128/spectrum.03805-23. Epub 2024 Mar 1.
4
Functional annotation of Candida albicans hypothetical proteins: a bioinformatics approach.白色念珠菌假定蛋白的功能注释：一种生物信息学方法。
Arch Microbiol. 2024 Feb 23;206(3):118. doi: 10.1007/s00203-024-03840-9.
5
Gut Microbiome Activity Contributes to Prediction of Individual Variation in Glycemic Response in Adults.肠道微生物群活性有助于预测成年人血糖反应的个体差异。
Diabetes Ther. 2022 Jan;13(1):89-111. doi: 10.1007/s13300-021-01174-z. Epub 2021 Nov 19.
6
Bacterial Responses to Glyoxal and Methylglyoxal: Reactive Electrophilic Species.细菌对乙二醛和甲基乙二醛的反应：活性亲电物质
Int J Mol Sci. 2017 Jan 17;18(1):169. doi: 10.3390/ijms18010169.
7
Linking Bacillus cereus Genotypes and Carbohydrate Utilization Capacity.蜡样芽孢杆菌基因型与碳水化合物利用能力的关联
PLoS One. 2016 Jun 7;11(6):e0156796. doi: 10.1371/journal.pone.0156796. eCollection 2016.
8
An L-Fucose Operon in the Probiotic Lactobacillus rhamnosus GG Is Involved in Adaptation to Gastrointestinal Conditions.益生菌鼠李糖乳杆菌GG中的L-岩藻糖操纵子参与对胃肠道环境的适应。
Appl Environ Microbiol. 2015 Jun;81(11):3880-8. doi: 10.1128/AEM.00260-15. Epub 2015 Mar 27.
9
Phenotypic and genotypic evidence for L-fucose utilization by Campylobacter jejuni.空肠弯曲菌利用 L-岩藻糖的表型和基因型证据。
J Bacteriol. 2011 Mar;193(5):1065-75. doi: 10.1128/JB.01252-10. Epub 2010 Dec 30.
10
Identification of lactaldehyde dehydrogenase in Methanocaldococcus jannaschii and its involvement in production of lactate for F420 biosynthesis.嗜热栖热甲烷球菌中乳醛脱氢酶的鉴定及其在F420生物合成中乳酸生成过程中的作用。
J Bacteriol. 2006 Apr;188(8):2836-44. doi: 10.1128/JB.188.8.2836-2844.2006.
本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
VIRULENCE OF ESCHERICHIA-SHIGELLA GENETIC HYBRIDS FOR THE GUINEA PIG.埃希氏菌-志贺氏菌基因杂种对豚鼠的毒力
J Bacteriol. 1963 Dec;86(6):1251-8. doi: 10.1128/jb.86.6.1251-1258.1963.
3
Transduction of lactose-utilizing ability among strains of E. coli and S. dysenteriae and the properties of the transducing phage particles.大肠杆菌和痢疾志贺氏菌菌株间乳糖利用能力的转导及转导噬菌体颗粒的特性
Virology. 1960 Nov;12:348-90. doi: 10.1016/0042-6822(60)90161-6.
4
Metabolism of L-fucose and L-rhamnose in Escherichia coli: differences in induction of propanediol oxidoreductase.大肠杆菌中L-岩藻糖和L-鼠李糖的代谢：1,2-丙二醇氧化还原酶诱导的差异
J Bacteriol. 1981 Jul;147(1):181-5. doi: 10.1128/jb.147.1.181-185.1981.
5
Two succinic semialdehyde dehydrogenases are induced when Escherichia coli K-12 Is grown on gamma-aminobutyrate.当大肠杆菌K-12在γ-氨基丁酸上生长时，会诱导产生两种琥珀酸半醛脱氢酶。
J Bacteriol. 1981 Mar;145(3):1425-7. doi: 10.1128/jb.145.3.1425-1427.1981.
6
An Escherichia coli mutant defective in the NAD-dependent succinate semialdehyde dehydrogenase.一种在依赖烟酰胺腺嘌呤二核苷酸的琥珀酸半醛脱氢酶方面存在缺陷的大肠杆菌突变体。
Arch Microbiol. 1982 Sep;132(3):270-5. doi: 10.1007/BF00407964.
7
Dual control of a common L-1,2-propanediol oxidoreductase by L-fucose and L-rhamnose in Escherichia coli.大肠杆菌中L-岩藻糖和L-鼠李糖对一种常见的L-1,2-丙二醇氧化还原酶的双重调控
J Bacteriol. 1984 Mar;157(3):828-32. doi: 10.1128/jb.157.3.828-832.1984.
8
Post-transcriptional control of L-1,2-propanediol oxidoreductase in the L-fucose pathway of Escherichia coli K-12.大肠杆菌K-12岩藻糖途径中L-1,2-丙二醇氧化还原酶的转录后调控
J Bacteriol. 1984 Jan;157(1):341-4. doi: 10.1128/jb.157.1.341-344.1984.
9
Constitutive activation of L-fucose genes by an unlinked mutation in Escherichia coli.大肠杆菌中一个不连锁突变导致L-岩藻糖基因的组成型激活。
J Bacteriol. 1984 Aug;159(2):725-9. doi: 10.1128/jb.159.2.725-729.1984.
10
Linkage map of Escherichia coli K-12, edition 7.大肠杆菌K-12连锁图谱，第7版。
Microbiol Rev. 1983 Jun;47(2):180-230. doi: 10.1128/mr.47.2.180-230.1983.
Zotero 插件