Dong Aiguo, Huo Junfeng, Yan Juanjuan, Dong Ailing
Shanxi Key Laboratory of Chinese Medicine Encephalopathy, Shanxi University of Chinese Medicine, Taiyuan, Shanxi Province, China.
Bureau of agriculture and rural affairs of Qianan, Tangshan, Hebei Province, China.
Environ Sci Pollut Res Int. 2021 Feb;28(6):6405-6410. doi: 10.1007/s11356-020-11017-2. Epub 2020 Sep 29.
The research was designed to examine oxidative stress of the liver of turtle Mauremys reevesii caused by cadmium (Cd). Turtles were injected intraperitoneally with cadmium at the concentration of 7.5, 15, and 30 mg/kg, and 5 turtles were taken from each group after exposure for 1 week (1 w), 2 weeks (2 w), and 3 weeks (3 w). The activities of SOD and CAT as well as the contents of GSH and MDA in liver tissues were detected by using a kit. The results showed that the difference between the control group and the Cd-treated group was statistically significant with the increase of Cd concentration and the prolongation of exposure time, which suggested that Cd caused oxidative stress on the liver of turtles.
本研究旨在探讨镉（Cd）对乌龟（黄喉拟水龟）肝脏的氧化应激作用。将乌龟按7.5、15和30 mg/kg的浓度腹腔注射镉，每组5只，分别在暴露1周（1 w）、2周（2 w）和3周（3 w）后取肝脏组织。采用试剂盒检测肝脏组织中SOD和CAT的活性以及GSH和MDA的含量。结果表明，随着镉浓度的增加和暴露时间的延长，对照组与镉处理组之间的差异具有统计学意义，提示镉对乌龟肝脏产生了氧化应激作用。
