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镉对中华鳖丙氨酸转氨酶和天门冬氨酸转氨酶活性及血浆总蛋白含量的影响。

Effects of cadmium on the activities of ALT and AST as well as the content of TP in plasma of freshwater turtle Mauremys reevesii.

机构信息

Shanxi Key Laboratory of Chinese Medicine Encephalopathy, Shanxi University of Chinese Medicine, Taiyuan, Shanxi Province, China.

Bureau of Agriculture and Rural Affairs of Qianan, Tangshan, Hebei Province, China.

出版信息

Environ Sci Pollut Res Int. 2020 May;27(15):18025-18028. doi: 10.1007/s11356-020-08338-7. Epub 2020 Mar 13.

Abstract

Cadmium (Cd) is one of the toxic metals in the aquatic environment. This study was designed to examine the effects of Cd on the activities of ALT and AST and the concentrations of TP in plasma of freshwater turtle Mauremys reevesii. Experiment turtles were exposed to Cd at the concentration of 15 mg/kg by intraperitoneal injection. The activities of ALT and AST and the concentrations of TP were investigated. Compared with the controls, the activities of ALT and AST in plasma of the treated turtles significantly increased. The concentrations of TP were comparable between the treated turtles and the controls except that were higher than the control turtles in 14 days (14 d) and 56 days (56 d). As a result that turtles exposed to Cd were led to liver function damage.

摘要

镉(Cd)是水生环境中的有毒金属之一。本研究旨在探讨镉对中华鳖(Mauremys reevesii)血浆中转氨酶(ALT 和 AST)活性和总蛋白(TP)浓度的影响。实验龟通过腹腔注射暴露于 15mg/kg 的镉。检测 ALT 和 AST 活性以及 TP 浓度。与对照组相比,处理组龟血浆中 ALT 和 AST 的活性显著升高。TP 浓度在处理组龟和对照组龟之间无差异,但在 14 天(14d)和 56 天(56d)时高于对照组龟。结果表明,镉暴露导致龟肝功能受损。

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