Bundoora Campus, Psychology and Counselling, La Trobe University, Bundoora, Australia.
Faculty of Science and Technology, School of Engineering, Deakin University, Melbourne, Australia.
Behav Res Methods. 2021 Jun;53(3):1115-1123. doi: 10.3758/s13428-020-01485-2. Epub 2020 Sep 28.
New technologies such as virtual reality (VR) and eye-tracking software have paved the way for more sophisticated and ecologically valid measures of cognitive function. Testing the sensitivity and reliability of such measurements in response to acute alcohol intoxication provides a first step in establishing how these measures may operate in relation to cognitive impairments observed post-concussion. Healthy young adults (N = 54, M = 20.65, SD = 2.06, 30 females) completed the CONVIRT test battery (manual simple and choice reaction-time and saccade reaction-time) at three breath alcohol concentration (BrAC) levels: 0.00%, 0.05%, 0.08%. Participants consumed alcoholic beverages at 30-min intervals, with BrAC monitored at 15-min intervals using a breathalyser. All three CONVIRT measures were sensitive to changes in cognitive performance induced by alcohol at BrAC levels at or exceeding 0.05%. A composite measure was also sensitive to alcohol intoxication (Cohen's d = .85 at BrAC = 0.05%; d = 1.20 at BrAC = 0.08%). Strong test-retest reliability was observed (all r < .80), with no gender differences noted. CONVIRT measures were reliable and detected dose-dependent changes in alcohol-induced cognitive impairment. Potentially, the ecologically valid measures may assist in better quantifying the effects of conditions such as concussion, on cognitive performance.
新技术，如虚拟现实（VR）和眼动追踪软件，为更复杂和生态有效的认知功能测量铺平了道路。测试这些测量方法在急性酒精中毒时的敏感性和可靠性，为了解这些测量方法如何与脑震荡后观察到的认知障碍相关联提供了第一步。健康的年轻成年人（N = 54，M = 20.65，SD = 2.06，女性 30 名）在三个呼吸酒精浓度（BrAC）水平下完成了 CONVIRT 测试电池（手动简单和选择反应时和眼跳反应时）：0.00%，0.05%，0.08%。参与者以 30 分钟的间隔饮酒，使用呼气酒精计以 15 分钟的间隔监测 BrAC。所有三个 CONVIRT 测量方法都对 0.05%或更高的 BrAC 水平的酒精引起的认知表现变化敏感。复合测量方法也对酒精中毒敏感（BrAC = 0.05%时的 Cohen's d =.85；BrAC = 0.08%时的 d = 1.20）。观察到强烈的测试-再测试可靠性（所有 r <.80），没有注意到性别差异。CONVIRT 测量方法可靠，可检测出酒精引起的认知障碍的剂量依赖性变化。潜在地，生态有效的测量方法可能有助于更好地量化脑震荡等情况对认知表现的影响。
