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评估 2011 年东日本大地震后 56388 名一线救援人员长期创伤后应激症状的相关因素。

Assessment of Factors Associated With Long-term Posttraumatic Stress Symptoms Among 56 388 First Responders After the 2011 Great East Japan Earthquake.

机构信息

Division of Behavioral Science, National Defense Medical College Research Institute, Tokorozawa City, Japan.

Department of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.

出版信息

JAMA Netw Open. 2020 Sep 1;3(9):e2018339. doi: 10.1001/jamanetworkopen.2020.18339.

Abstract

IMPORTANCE

First responders are at risk for developing symptoms of posttraumatic stress disorder (PTSD). Little is known about the risk factors for developing PTSD during a years-long period after complex mass disasters.

OBJECTIVE

To explore the long-term course of PTSD symptoms and to identify risk factors and their relative association with PTSD among first responders dispatched to the 2011 Japanese earthquake, tsunami, and nuclear disaster.

DESIGN, SETTING, AND PARTICIPANTS: This 6-year, large, prospective cohort study was part of a continuous longitudinal study of Japan Ground Self-Defense Force first responders. The data were collected at 1, 6, 12, 24, 36, 48, 60, and 72 months after mission completion from 2011 to 2017. Of approximately 70 000 eligible participants, 56 388 were enrolled in this study. Data were analyzed from 2017 to 2020.

EXPOSURES

Stress exposures owing to personal or professional disaster experience (eg, duties with body recovery or radiation exposure risk) and working conditions (eg, deployment length, postdeployment overtime work).

MAIN OUTCOMES AND MEASURES

The Impact of Event Scale-Revised score assessed PTSD symptoms; scores of at least 25 were defined as probable PTSD. Cox proportional hazards regression models assessed the risk factors for incidence of probable PTSD.

RESULTS

Among the 56 388 participants, 97.1% were men, and the median age at enrollment was 34 (range, 18-63) years. A probable PTSD rate was 2.7% at 1 month and showed a downward trend in the first year and a subsequent plateau. The cumulative incidence of probable PTSD was 6.75%. The severity of PTSD symptoms demonstrated a high degree of rank-order stability over time. Rather than professional disaster experience, sociodemographic factors and working conditions were independently associated with the incidence of probable PTSD: personal experience of the disaster (hazard ratio [HR], 1.96; 95% CI, 1.72-2.24), deployment length of at least 3 months (HR vs <1 month, 1.75; 95% CI, 1.52-2.02), increased age (HR for ≥46 vs ≤25 years, 2.28; 95% CI, 1.79-2.92), and postdeployment overtime work of at least 3 months (HR vs little to none, 1.61; 95% CI, 1.39-1.87).

CONCLUSIONS AND RELEVANCE

Given these findings, in the future, first responders' PTSD symptoms might be mitigated by shortening deployment length, avoiding postdeployment overtime work, and paying special attention to the needs of personnel with personal experience of the disaster or older age. Efforts to alleviate responders' initial symptoms will be required.

摘要

重要性

急救人员有出现创伤后应激障碍(PTSD)症状的风险。对于在复杂的大规模灾害发生后的多年时间里,急救人员出现 PTSD 的风险因素知之甚少。

目的

探讨 PTSD 症状的长期病程,并确定在被派往 2011 年日本地震、海啸和核灾难的急救人员中,与 PTSD 相关的风险因素及其相对关联。

设计、地点和参与者:这是一项为期 6 年的大型前瞻性队列研究,是日本自卫队急救人员连续纵向研究的一部分。数据于 2011 年至 2017 年期间在任务完成后的 1、6、12、24、36、48、60 和 72 个月进行收集。在大约 70000 名符合条件的参与者中,有 56388 人参加了这项研究。数据于 2017 年至 2020 年进行分析。

暴露

因个人或职业灾难经历(例如,参与遗体恢复或有辐射暴露风险的职责)和工作条件(例如,部署时间、部署后加班工作)而导致的应激暴露。

主要结果和测量

修订后的事件影响量表(IES-R)评分评估 PTSD 症状;得分至少为 25 分被定义为可能患有 PTSD。Cox 比例风险回归模型评估了 PTSD 发生率的风险因素。

结果

在 56388 名参与者中,97.1%为男性,入组时的中位年龄为 34 岁(范围,18-63 岁)。1 个月时 PTSD 的患病率为 2.7%,在第一年呈下降趋势,随后趋于平稳。可能患有 PTSD 的累积发病率为 6.75%。PTSD 症状的严重程度随着时间的推移表现出高度的等级稳定性。与职业灾难经历相比,社会人口学因素和工作条件与 PTSD 的发生独立相关:个人经历灾难(危险比[HR],1.96;95%CI,1.72-2.24)、至少 3 个月的部署(HR 与 <1 个月,1.75;95%CI,1.52-2.02)、年龄增长(HR 为≥46 岁与≤25 岁,2.28;95%CI,1.79-2.92)和至少 3 个月的部署后加班工作(HR 与几乎没有或没有加班工作,1.61;95%CI,1.39-1.87)。

结论和相关性

鉴于这些发现,未来可能通过缩短部署时间、避免部署后加班工作以及特别关注有个人灾难经历或年龄较大的人员的需求,来减轻急救人员的 PTSD 症状。需要努力减轻急救人员的初始症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153d/7525349/8cac40330998/jamanetwopen-e2018339-g001.jpg

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