Lee Hung Pang, Gaharwar Akhilesh K
Biomedical Engineering College of Engineering Texas A&M University College Station TX 77843 USA.
Material Science and Engineering College of Engineering Texas A&M University College Station TX 77843 USA.
Adv Sci (Weinh). 2020 Jul 17;7(17):2000863. doi: 10.1002/advs.202000863. eCollection 2020 Sep.
Light-responsive inorganic biomaterials are an emerging class of materials used for developing noninvasive, noncontact, precise, and controllable medical devices in a wide range of biomedical applications, including photothermal therapy, photodynamic therapy, drug delivery, and regenerative medicine. Herein, a range of biomaterials is discussed, including carbon-based nanomaterials, gold nanoparticles, graphite carbon nitride, transition metal dichalcogenides, and up-conversion nanoparticles that are used in the design of light-responsive medical devices. The importance of these light-responsive biomaterials is explored to design light-guided nanovehicle, modulate cellular behavior, as well as regulate extracellular microenvironments. Additionally, future perspectives on the clinical use of light-responsive biomaterials are highlighted.
光响应性无机生物材料是一类新兴材料,用于开发广泛生物医学应用中的无创、非接触、精确且可控的医疗设备,包括光热疗法、光动力疗法、药物递送和再生医学。本文讨论了一系列生物材料,包括用于光响应性医疗设备设计的碳基纳米材料、金纳米颗粒、石墨氮化碳、过渡金属二硫属化物和上转换纳米颗粒。探讨了这些光响应性生物材料在设计光导纳米载体、调节细胞行为以及调控细胞外微环境方面的重要性。此外,还强调了光响应性生物材料临床应用的未来前景。