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用于生物医学应用的光响应性无机生物材料。

Light-Responsive Inorganic Biomaterials for Biomedical Applications.

作者信息

Lee Hung Pang, Gaharwar Akhilesh K

机构信息

Biomedical Engineering College of Engineering Texas A&M University College Station TX 77843 USA.

Material Science and Engineering College of Engineering Texas A&M University College Station TX 77843 USA.

出版信息

Adv Sci (Weinh). 2020 Jul 17;7(17):2000863. doi: 10.1002/advs.202000863. eCollection 2020 Sep.

DOI:10.1002/advs.202000863
PMID:32995121
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7507067/
Abstract

Light-responsive inorganic biomaterials are an emerging class of materials used for developing noninvasive, noncontact, precise, and controllable medical devices in a wide range of biomedical applications, including photothermal therapy, photodynamic therapy, drug delivery, and regenerative medicine. Herein, a range of biomaterials is discussed, including carbon-based nanomaterials, gold nanoparticles, graphite carbon nitride, transition metal dichalcogenides, and up-conversion nanoparticles that are used in the design of light-responsive medical devices. The importance of these light-responsive biomaterials is explored to design light-guided nanovehicle, modulate cellular behavior, as well as regulate extracellular microenvironments. Additionally, future perspectives on the clinical use of light-responsive biomaterials are highlighted.

摘要

光响应性无机生物材料是一类新兴材料，用于开发广泛生物医学应用中的无创、非接触、精确且可控的医疗设备，包括光热疗法、光动力疗法、药物递送和再生医学。本文讨论了一系列生物材料，包括用于光响应性医疗设备设计的碳基纳米材料、金纳米颗粒、石墨氮化碳、过渡金属二硫属化物和上转换纳米颗粒。探讨了这些光响应性生物材料在设计光导纳米载体、调节细胞行为以及调控细胞外微环境方面的重要性。此外，还强调了光响应性生物材料临床应用的未来前景。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f41/7507067/f9a695d2f871/ADVS-7-2000863-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f41/7507067/a3d0bc10c336/ADVS-7-2000863-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f41/7507067/80084b3c8d36/ADVS-7-2000863-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f41/7507067/75492d9aa3f8/ADVS-7-2000863-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f41/7507067/c6aba7a6d174/ADVS-7-2000863-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f41/7507067/03eee88c6d23/ADVS-7-2000863-g009.jpg

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