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Bringing Gene Therapies for HIV Disease to Resource-Limited Parts of the World.

作者信息

McCune Joseph M, Turner Emily H, Jiang Adam, Doehle Brian P

机构信息

HIV Frontiers, Global Health Innovative Technology Solutions, Bill & Melinda Gates Foundation, Seattle, Washington, USA.

出版信息

Hum Gene Ther. 2021 Jan;32(1-2):21-30. doi: 10.1089/hum.2020.252. Epub 2020 Oct 30.

DOI:10.1089/hum.2020.252
PMID:32998595
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10112459/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d02/10112459/c983326a99d3/hum.2020.252_figure3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d02/10112459/8f44cd929a81/hum.2020.252_figure1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d02/10112459/ba56c5b432b7/hum.2020.252_figure2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d02/10112459/c983326a99d3/hum.2020.252_figure3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d02/10112459/8f44cd929a81/hum.2020.252_figure1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d02/10112459/ba56c5b432b7/hum.2020.252_figure2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d02/10112459/c983326a99d3/hum.2020.252_figure3.jpg

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Advances in gene therapy for hematologic disease and considerations for transfusion medicine.血液疾病的基因治疗进展及输血医学相关考虑。
Semin Hematol. 2020 Apr;57(2):83-91. doi: 10.1053/j.seminhematol.2020.07.004. Epub 2020 Jul 28.
2
Distinct viral reservoirs in individuals with spontaneous control of HIV-1.个体中 HIV-1 自发性控制的独特病毒储库。
Nature. 2020 Sep;585(7824):261-267. doi: 10.1038/s41586-020-2651-8. Epub 2020 Aug 26.
3
Recent Advances in the Treatment of Sickle Cell Disease.镰状细胞病治疗的最新进展
长效治疗对 HIV 的长期影响和价值:建模分析。
J Int AIDS Soc. 2023 Sep;26(9):e26170. doi: 10.1002/jia2.26170.
4
Ethical and practical considerations for cell and gene therapy toward an HIV cure: findings from a qualitative in-depth interview study in the United States.细胞和基因治疗实现 HIV 治愈的伦理与实践考量:来自美国深入定性访谈研究的发现。
BMC Med Ethics. 2022 Apr 9;23(1):39. doi: 10.1186/s12910-022-00780-1.
5
Collaborative science to advance gene therapies in resource-limited parts of the world.开展合作科研,推动在世界资源匮乏地区的基因治疗。
Mol Ther. 2021 Nov 3;29(11):3101-3102. doi: 10.1016/j.ymthe.2021.05.024. Epub 2021 Aug 30.
Front Physiol. 2020 May 20;11:435. doi: 10.3389/fphys.2020.00435. eCollection 2020.
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TIGIT Blockade: A Multipronged Approach to Target the HIV Reservoir.TIGIT阻断:一种针对HIV储存库的多管齐下方法。
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5
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