Kelly J K, Pai C H, Jadusingh I H, Macinnis M L, Shaffer E A, Hershfield N B
Am J Clin Pathol. 1987 Jul;88(1):78-82. doi: 10.1093/ajcp/88.1.78.
The histopathology of rectosigmoid biopsies from 20 patients with bloody diarrhea resulting from verotoxin-producing Escherichia coli infection is reported. The biopsies displayed a range of appearances, from normal to mild, nonspecific inflammation to acute infectious-type colitis. Surface-adherent or invasive bacteria were not identified. The morphologic features of infectious colitis and the absence of bacteria suggest that verotoxin may be responsible for the pathologic changes.
