Zhou Jianchuan, Ao Xiang, Lei Yuanpei, Ji Cheng, Ma Qiugang
State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing, 100193, China.
Anim Nutr. 2020 Sep;6(3):372-378. doi: 10.1016/j.aninu.2020.03.011. Epub 2020 Jul 6.
This study was conducted to evaluate the alleviation of ANSB01G culture as zearalenone (ZEA) biodegradation agent on oxidative stress, cell apoptosis and fecal ZEA residue in the first parity gestation sows during the gestation. A total of 80 first-parity gilts (Yorkshire × Landrace) were randomly allocated to 4 dietary treatments with 20 replications per treatment and one gilt per replicate. The dietary treatments were as follows: CO (positive control); MO (negative control, ZEA level at 246 μg/kg diet); COA (CO + ANSB01G culture with 2 × 10 CFU/kg diet); MOA (MO + ZEA level at 260 μg/kg diet + ANSB01G culture with 2 × 10 CFU/kg diet). The experiment lasted for the whole gestation period of sows. Results showed that feeding the diet naturally contaminated with low-dose ZEA caused an increase of cell apoptosis in organ and the residual ZEA in feces as well as a decrease of antioxidant function in serum. The addition of ANSB01G culture in the diets can effectively alleviate the status of oxidative stress and cell apoptosis induced by ZEA in diets of gestation sows, as well as decrease the content of residual ZEA in feces.
本研究旨在评估作为玉米赤霉烯酮（ZEA）生物降解剂的ANSB01G培养物对初产妊娠母猪妊娠期氧化应激、细胞凋亡和粪便ZEA残留的缓解作用。总共80头初产小母猪（约克夏×长白）被随机分配到4种日粮处理组，每组20个重复，每个重复1头小母猪。日粮处理如下：CO（阳性对照）；MO（阴性对照，日粮中ZEA水平为246μg/kg）；COA（CO+日粮中添加2×10CFU/kg的ANSB01G培养物）；MOA（MO+日粮中ZEA水平为260μg/kg+日粮中添加2×10CFU/kg的ANSB01G培养物）。实验持续整个母猪妊娠期。结果表明，饲喂天然受低剂量ZEA污染的日粮会导致器官细胞凋亡增加、粪便中ZEA残留增加以及血清抗氧化功能下降。日粮中添加ANSB01G培养物可有效缓解妊娠期母猪日粮中ZEA诱导的氧化应激和细胞凋亡状态，并降低粪便中ZEA残留量。
