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How NETosis could drive "Post-COVID-19 syndrome" among survivors.

作者信息

Sawadogo Serge A, Dighero-Kemp Bonnie, Ouédraogo Dieu-Donné, Hensley Lisa, Sakandé Jean

机构信息

Université Joseph Ki Zerbo, Unité de Formation et de Recherche en Sciences de la Santé, 03 BP 7021 Ouagadougou 03, Burkina Faso; Institut pour la Promotion de la Recherche et de l'Innovation en Immunologie Médicale de Ouagadougou (PrïmO) site Nelson Mandela, Immunology department, 09 BP 706, Ouagadougou 09, Burkina Faso.

National Institute of Allergy and Infectious Diseases (NIAID) Integrated Research Facility Division of Clinical Research, Virology Department, 8200 Research Plaza Fort Detrick, MD, 21702, United States.

出版信息

Immunol Lett. 2020 Dec;228:35-37. doi: 10.1016/j.imlet.2020.09.005. Epub 2020 Sep 29.

DOI:10.1016/j.imlet.2020.09.005
PMID:33007368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7524448/
Abstract
摘要

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Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis.COVID-19 炎症与 C5a-C5aR1 轴的激活有关。
Nature. 2020 Dec;588(7836):146-150. doi: 10.1038/s41586-020-2600-6. Epub 2020 Jul 29.
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Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections.严重的免疫抑制，而非细胞因子风暴，是 COVID-19 感染的特征。
JCI Insight. 2020 Sep 3;5(17):140329. doi: 10.1172/jci.insight.140329.
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A comparison of mortality-related risk factors of COVID-19, SARS, and MERS: A systematic review and meta-analysis.新冠病毒、严重急性呼吸综合征和中东呼吸综合征病死率相关危险因素的比较：系统评价和荟萃分析。
J Infect. 2020 Oct;81(4):e18-e25. doi: 10.1016/j.jinf.2020.07.002. Epub 2020 Jul 4.
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Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial.雾化吸入重组人脱氧核糖核酸酶治疗新型冠状病毒肺炎所致急性呼吸窘迫综合征患者的疗效和安全性：一项随机对照试验的研究方案的结构化总结。
Trials. 2020 Jun 19;21(1):548. doi: 10.1186/s13063-020-04488-8.
6
SARS-CoV2 may evade innate immune response, causing uncontrolled neutrophil extracellular traps formation and multi-organ failure.SARS-CoV2 可能逃避先天免疫反应，导致不受控制的中性粒细胞胞外诱捕网形成和多器官衰竭。
Clin Sci (Lond). 2020 Jun 26;134(12):1295-1300. doi: 10.1042/CS20200531.
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Hematological features of persons with COVID-19.新型冠状病毒肺炎患者的血液学特征。
Leukemia. 2020 Aug;34(8):2163-2172. doi: 10.1038/s41375-020-0910-1. Epub 2020 Jun 11.
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Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19.中性粒细胞和中性粒细胞胞外诱捕网驱动 COVID-19 的坏死性炎症。
Cells. 2020 Jun 2;9(6):1383. doi: 10.3390/cells9061383.
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Hematological findings in coronavirus disease 2019: indications of progression of disease.2019 年冠状病毒病的血液学表现：疾病进展的迹象。
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J Autoimmun. 2020 Sep;113:102484. doi: 10.1016/j.jaut.2020.102484. Epub 2020 May 23.