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尼日尔一名患有严重急性营养不良的婴儿在儿科病房感染新冠病毒死亡病例

A Fatal Case of COVID-19 in an Infant with Severe Acute Malnutrition Admitted to a Paediatric Ward in Niger.

作者信息

Soumana Alido, Samaila Aboubacar, Moustapha Lamine Mahaman, Kamaye Moumouni, Daouda Balkissa, Salifou Ibrahim Alkassoum, Lagare Adamou, Adehossi Eric Omar, Ibrahim Maman Laminou

机构信息

Department of Pediatrics, Amirou Boubacar Diallo National Hospital of Niamey, Niamey, Niger.

Sciences of Health Faculty, Abdou Moumouni University of Niamey, Niamey, Niger.

出版信息

Case Rep Pediatr. 2020 Sep 24;2020:8847415. doi: 10.1155/2020/8847415. eCollection 2020.

Abstract

While there have been very few fatal cases, SARS-CoV-2 has been reported in paediatric patients. This study aims to describe a fatal case of COVID-19 in a child with severe acute malnutrition. The eight-month-old child presented with fever, diarrhoea, and difficulty in breathing. The mother of the child had fever and shortness of breath four weeks before she died. Physical examination revealed lethargy, dehydration, and severe weight loss with a weight of 5 kg at a height of 78 cm tall. The weight-for-height index was less than three -scores, which corresponds to severe acute malnutrition. The pulmonary examination revealed moderate respiratory distress, and the chest X-ray presented features suggestive of pneumonia in the right lung area. In the context of the COVID-19 outbreak in Niger and the circumstances of the mother's death, a nasal swab was taken for laboratory confirmation. Treatment provided to the child included intranasal oxygen, antibiotics, and a dietary program with therapeutic milk. The child died 48 hours after his admission. The history of contact with a SARS-CoV-2 suspect or positive patient should lead to screening for infection by using RT-PCR. It is important to investigate malnutrition as a potential risk factor for severe SARS-CoV-2 infection and resultant mortality.

摘要

虽然致命病例非常少,但儿科患者中已报告感染了严重急性呼吸综合征冠状病毒2(SARS-CoV-2)。本研究旨在描述一例患有严重急性营养不良儿童的COVID-19致命病例。这名八个月大的儿童出现发热、腹泻和呼吸困难。孩子的母亲在去世前四周出现发热和呼吸急促。体格检查发现嗜睡、脱水和严重体重减轻,身高78厘米,体重5千克。身高别体重指数低于三个标准差,这相当于严重急性营养不良。肺部检查发现中度呼吸窘迫,胸部X光显示右肺区域有肺炎迹象。鉴于尼日尔爆发COVID-19以及母亲的死亡情况,采集了鼻拭子进行实验室确诊。给予该儿童的治疗包括鼻内输氧、抗生素以及含治疗性奶粉的饮食方案。该儿童入院48小时后死亡。接触SARS-CoV-2疑似或阳性患者的病史应促使通过逆转录聚合酶链反应(RT-PCR)进行感染筛查。调查营养不良作为严重SARS-CoV-2感染及由此导致死亡的潜在危险因素很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1db0/7520010/5b19bc7cbf6e/CRIPE2020-8847415.001.jpg

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