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南非农村地区 COVID-19 封锁期间的基本医疗保健可及性:一项中断时间序列分析。

Access to primary healthcare during lockdown measures for COVID-19 in rural South Africa: an interrupted time series analysis.

机构信息

Clinical Research Department, Africa Health Research Institute, Durban, Kwa-Zulu Natal, South Africa

Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.

出版信息

BMJ Open. 2020 Oct 5;10(10):e043763. doi: 10.1136/bmjopen-2020-043763.

Abstract

OBJECTIVES

We evaluated whether implementation of lockdown orders in South Africa affected ambulatory clinic visitation in rural Kwa-Zulu Natal (KZN).

DESIGN

Observational cohort SETTING: Data were analysed from 11 primary healthcare clinics in northern KZN.

PARTICIPANTS

A total of 46 523 individuals made 89 476 clinic visits during the observation period.

EXPOSURE OF INTEREST

We conducted an interrupted time series analysis to estimate changes in clinic visitation with a focus on transitions from the prelockdown to the level 5, 4 and 3 lockdown periods.

OUTCOME MEASURES

Daily clinic visitation at ambulatory clinics. In stratified analyses, we assessed visitation for the following subcategories: child health, perinatal care and family planning, HIV services, non-communicable diseases and by age and sex strata.

RESULTS

We found no change in total clinic visits/clinic/day at the time of implementation of the level 5 lockdown (change from 90.3 to 84.6 mean visits/clinic/day, 95% CI -16.5 to 3.1), or at the transitions to less stringent level 4 and 3 lockdown levels. We did detect a >50% reduction in child healthcare visits at the start of the level 5 lockdown from 11.9 to 4.7 visits/day (-7.1 visits/clinic/day, 95% CI -8.9 to 5.3), both for children aged <1 year and 1-5 years, with a gradual return to prelockdown within 3 months after the first lockdown measure. In contrast, we found no drop in clinic visitation in adults at the start of the level 5 lockdown, or related to HIV care (from 37.5 to 45.6, 8.0 visits/clinic/day, 95% CI 2.1 to 13.8).

CONCLUSIONS

In rural KZN, we identified a significant, although temporary, reduction in child healthcare visitation but general resilience of adult ambulatory care provision during the first 4 months of the lockdown. Future work should explore the impacts of the circulating epidemic on primary care provision and long-term impacts of reduced child visitation on outcomes in the region.

摘要

目的

我们评估了南非实施封锁令是否对夸祖鲁-纳塔尔省(Kwa-Zulu Natal,KZN)农村地区的门诊就诊产生影响。

设计

观察性队列研究

地点

数据分析来自 KZN 北部的 11 个初级保健诊所。

参与者

在观察期间,共有 46523 人进行了 89476 次诊所就诊。

暴露因素

我们进行了一项中断时间序列分析,以评估诊所就诊量的变化,重点关注从封锁前到封锁级别 5、4 和 3 的过渡时期。

结果

我们没有发现实施 5 级封锁时总就诊量/诊所/天的变化(从 90.3 次就诊/诊所/天变为 84.6 次平均就诊/诊所/天,95%置信区间为-16.5 至 3.1),或在向限制较宽松的 4 级和 3 级封锁水平过渡时也没有变化。我们确实发现,在 5 级封锁开始时,儿童保健就诊量下降了超过 50%,从每天 11.9 次就诊减少到 4.7 次就诊(每天减少 7.1 次就诊/诊所,95%置信区间为-8.9 至 5.3),无论是 1 岁以下还是 1-5 岁的儿童,在首次封锁措施实施 3 个月后,就诊量逐渐恢复到封锁前水平。相比之下,我们没有发现 5 级封锁开始时成年人的就诊量下降,也没有发现与艾滋病毒护理相关的就诊量下降(从 37.5 次就诊增加到 45.6 次就诊,8.0 次就诊/诊所/天,95%置信区间为 2.1 至 13.8)。

结论

在 KZN 农村地区,我们发现尽管是暂时的,但在封锁的前 4 个月,儿童保健就诊量显著减少,但成人门诊护理的总体供应仍具有弹性。未来的研究应探讨当前流行对初级保健服务的影响,以及儿童就诊量减少对该地区结果的长期影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3714/7536636/13d2ec5f38f9/bmjopen-2020-043763f01.jpg

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