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局部细菌疗法——反复呼吸道感染有希望的预防手段。

Local Bacteriotherapy - a promising preventive tool in recurrent respiratory infections.

机构信息

Allergy Clinic, Casa di Cura Villa Montallegro , Genoa, Italy.

ENT Department, University of Catania , Catania, Italy.

出版信息

Expert Rev Clin Immunol. 2020 Nov;16(11):1047-1052. doi: 10.1080/1744666X.2021.1833720. Epub 2020 Oct 15.

Abstract

INTRODUCTION

Children with recurrent respiratory infections (RRI) represent a social issue for the economic burden and the negative family impact. Local Bacteriotherapy is an attractive therapeutic strategy that could be potentially effective in preventing infections. The current article remarks on the existing evidence of preventing RRI by Local Bacteriotherapy.

AREAS COVERED

The literature search methodology was based on the articles cited by PubMed from 1980 to 2020. Respiratory infections include rhino-pharyngitis, otitis media, rhinosinusitis, pharyngo-tracheitis, bronchitis, and pneumonia. Several studies were performed to investigate the effects of Local Bacteriotherapy in children with RRI. Both intranasal and oral Local Bacteriotherapy were evaluated. The findings showed that Local Bacteriotherapy significantly reduced the number of RI episodes, their severity, the use of antibiotics, and school absences.

EXPERT OPINION

Local Bacteriotherapy is a promising approach to RRI prevention and could be a profitable strategy to contrast infections in the future.

摘要

简介

反复呼吸道感染(RRI)的儿童给家庭带来了经济负担和负面影响,这是一个社会问题。局部细菌疗法是一种有吸引力的治疗策略,可能对预防感染有潜在的效果。本文主要讨论了局部细菌疗法预防 RRI 的现有证据。

涵盖领域

文献检索方法基于 1980 年至 2020 年 PubMed 引用的文章。呼吸道感染包括鼻咽炎、中耳炎、鼻-鼻窦炎、咽-气管炎、支气管炎和肺炎。已经进行了多项研究来调查局部细菌疗法对 RRI 儿童的影响。评估了鼻腔内和口服局部细菌疗法。结果表明,局部细菌疗法可显著减少 RI 发作次数、严重程度、抗生素使用和缺课。

专家意见

局部细菌疗法是预防 RRI 的一种很有前途的方法,将来可能是一种对抗感染的有利策略。

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