• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The role for the metagenome in the pathogenesis of COVID-19.

作者信息

Friedland Robert P, Haribabu Bodduluri

机构信息

Department of Neurology, University of Louisville School of Medicine, Louisville, KY 40202, United States.

Department of Microbiology and Immunology, University of Louisville School of Medicine, Louisville, KY 40202, United States.

出版信息

EBioMedicine. 2020 Nov;61:103019. doi: 10.1016/j.ebiom.2020.103019. Epub 2020 Oct 7.

DOI:10.1016/j.ebiom.2020.103019
PMID:33038769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7538391/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e09f/7554025/087e8f7f0e26/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e09f/7554025/087e8f7f0e26/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e09f/7554025/087e8f7f0e26/gr1.jpg

相似文献

1
The role for the metagenome in the pathogenesis of COVID-19.宏基因组在新冠病毒疾病发病机制中的作用。
EBioMedicine. 2020 Nov;61:103019. doi: 10.1016/j.ebiom.2020.103019. Epub 2020 Oct 7.
2
MetCap: a bioinformatics probe design pipeline for large-scale targeted metagenomics.MetCap：一种用于大规模靶向宏基因组学的生物信息学探针设计流程
BMC Bioinformatics. 2015 Feb 28;16(1):65. doi: 10.1186/s12859-015-0501-8.
3
Metagenome Analysis: a Powerful Tool for Enzyme Bioprospecting.宏基因组分析：酶生物勘探的强大工具。
Appl Biochem Biotechnol. 2017 Oct;183(2):636-651. doi: 10.1007/s12010-017-2568-3. Epub 2017 Aug 16.
4
Databases of the marine metagenomics.海洋宏基因组学数据库。
Gene. 2016 Feb 1;576(2 Pt 1):724-8. doi: 10.1016/j.gene.2015.10.035. Epub 2015 Oct 28.
5
Functional Metagenomics Reveals an Overlooked Diversity and Novel Features of Soil-Derived Bacterial Phosphatases and Phytases.功能宏基因组学揭示了土壤来源的细菌磷酸酶和植酸酶被忽视的多样性和新特征。
mBio. 2019 Jan 29;10(1):e01966-18. doi: 10.1128/mBio.01966-18.
6
Long-read metagenomics retrieves complete single-contig bacterial genomes from canine feces.长读宏基因组从犬粪便中获得完整的单菌基因组。
BMC Genomics. 2021 May 6;22(1):330. doi: 10.1186/s12864-021-07607-0.
7
Exploration of activated sludge resistome using metagenomics.利用宏基因组学探索活性污泥的抗药组。
Sci Total Environ. 2019 Nov 20;692:1155-1164. doi: 10.1016/j.scitotenv.2019.07.267. Epub 2019 Jul 18.
8
[Latest progress in unveiling the oral microbial metagenome].[揭示口腔微生物宏基因组的最新进展]
Hua Xi Kou Qiang Yi Xue Za Zhi. 2013 Feb;31(1):107-11.
9
Prediction and analysis of metagenomic operons via MetaRon: a pipeline for prediction of Metagenome and whole-genome opeRons.通过 MetaRon 预测和分析宏基因组操纵子：用于预测宏基因组和全基因组操纵子的管道。
BMC Genomics. 2021 Jan 19;22(1):60. doi: 10.1186/s12864-020-07357-5.
10
Metagenomics methods for the study of plant-associated microbial communities: A review.宏基因组学方法在植物相关微生物群落研究中的应用：综述。
J Microbiol Methods. 2020 Mar;170:105860. doi: 10.1016/j.mimet.2020.105860. Epub 2020 Feb 4.

引用本文的文献

1
The gut virome and human health: From diversity to personalized medicine.肠道病毒组与人类健康：从多样性到个性化医学。
Eng Microbiol. 2025 Feb 7;5(1):100191. doi: 10.1016/j.engmic.2025.100191. eCollection 2025 Mar.
2
Alterations of the gut commensal in patients with COVID-19.新冠病毒疾病（COVID-19）患者肠道共生菌的改变
Virulence. 2025 Dec;16(1):2505999. doi: 10.1080/21505594.2025.2505999. Epub 2025 May 18.
3
The Link between Inflammation, Lipid Derivatives, and Microbiota Metabolites in COVID-19 Patients: Implications on Eating Behaviors and Nutritional Status.

本文引用的文献

1
The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis.口腔与肠道共生菌驱动的结肠炎中的黏膜连接。
Cell. 2020 Jul 23;182(2):447-462.e14. doi: 10.1016/j.cell.2020.05.048. Epub 2020 Jun 16.
2
Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans.未暴露于 SARS-CoV-2 人群中的选择性和交叉反应性 T 细胞表位。
Science. 2020 Oct 2;370(6512):89-94. doi: 10.1126/science.abd3871. Epub 2020 Aug 4.
3
Immune Response, Inflammation, and the Clinical Spectrum of COVID-19.免疫反应、炎症与 COVID-19 的临床谱。
COVID-19 患者炎症、脂类衍生物与肠道菌群代谢物之间的关联：对饮食行为和营养状况的影响。
Int J Mol Sci. 2024 Jul 19;25(14):7899. doi: 10.3390/ijms25147899.
4
COVID-19 alters human microbiomes: a meta-analysis.COVID-19 改变人类微生物组：一项荟萃分析。
Front Cell Infect Microbiol. 2023 Aug 2;13:1211348. doi: 10.3389/fcimb.2023.1211348. eCollection 2023.
5
Microbiome analysis revealing microbial interactions and secondary bacterial infections in COVID-19 patients comorbidly affected by Type 2 diabetes.微生物组分析揭示了 2 型糖尿病合并 COVID-19 患者的微生物相互作用和继发细菌感染。
J Med Virol. 2023 Jan;95(1):e28234. doi: 10.1002/jmv.28234. Epub 2022 Nov 1.
6
Nasopharyngeal microbiome of COVID-19 patients revealed a distinct bacterial profile in deceased and recovered individuals.新冠病毒感染者鼻咽微生物组揭示了死亡和康复个体中独特的细菌特征。
Microb Pathog. 2022 Dec;173(Pt A):105829. doi: 10.1016/j.micpath.2022.105829. Epub 2022 Oct 15.
7
Characterization of the Upper Respiratory Bacterial Microbiome in Critically Ill COVID-19 Patients.危重症 COVID-19 患者上呼吸道细菌微生物群的特征分析
Biomedicines. 2022 Apr 23;10(5):982. doi: 10.3390/biomedicines10050982.
8
Molecular signature of postmortem lung tissue from COVID-19 patients suggests distinct trajectories driving mortality.COVID-19 患者死后肺组织的分子特征表明存在不同的死亡驱动轨迹。
Dis Model Mech. 2022 May 1;15(5). doi: 10.1242/dmm.049572. Epub 2022 Jun 6.
9
The Human Virome: Viral Metagenomics, Relations with Human Diseases, and Therapeutic Applications.人类病毒组：病毒宏基因组学、与人类疾病的关系及治疗应用。
Viruses. 2022 Jan 28;14(2):278. doi: 10.3390/v14020278.
10
Gut and airway microbiota and their role in COVID-19 infection and pathogenesis: a scoping review.肠道和气道微生物群及其在 COVID-19 感染和发病机制中的作用：范围综述。
Infection. 2022 Aug;50(4):815-847. doi: 10.1007/s15010-021-01715-5. Epub 2021 Oct 20.
Front Immunol. 2020 Jun 16;11:1441. doi: 10.3389/fimmu.2020.01441. eCollection 2020.
4
Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals.COVID-19 疾病患者和未接触者体内针对 SARS-CoV-2 冠状病毒的 T 细胞反应的靶标。
Cell. 2020 Jun 25;181(7):1489-1501.e15. doi: 10.1016/j.cell.2020.05.015. Epub 2020 May 20.
5
The Innate Immune System: Fighting on the Front Lines or Fanning the Flames of COVID-19?先天性免疫系统：是在前线作战还是助长 COVID-19 的火势？
Cell Host Microbe. 2020 Jun 10;27(6):863-869. doi: 10.1016/j.chom.2020.05.009. Epub 2020 May 20.
6
Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study.纽约市 5279 例 2019 年冠状病毒病患者住院和重症的相关因素：前瞻性队列研究。
BMJ. 2020 May 22;369:m1966. doi: 10.1136/bmj.m1966.
7
Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.中国武汉严重 COVID-19 患者的临床病程和结局：一项单中心、回顾性、观察性研究。
Lancet Respir Med. 2020 May;8(5):475-481. doi: 10.1016/S2213-2600(20)30079-5. Epub 2020 Feb 24.
8
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia.新型冠状病毒感染肺炎在中国武汉的早期传播动力学。
N Engl J Med. 2020 Mar 26;382(13):1199-1207. doi: 10.1056/NEJMoa2001316. Epub 2020 Jan 29.
9
The intestinal microbiota fuelling metabolic inflammation.肠道微生物群促进代谢性炎症。
Nat Rev Immunol. 2020 Jan;20(1):40-54. doi: 10.1038/s41577-019-0198-4. Epub 2019 Aug 6.
10
Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection.菌群驱动的肺间质细胞中的持续干扰素信号可预防流感病毒感染。
Cell Rep. 2019 Jul 2;28(1):245-256.e4. doi: 10.1016/j.celrep.2019.05.105.