Department of Surgery, Faculty of Medicine, Kuwait University, Kuwait, Kuwait.
Department of MLS, Faculty of Allied Health Science, Kuwait University, Kuwait, Kuwait,
Med Princ Pract. 2021;30(3):223-235. doi: 10.1159/000512142. Epub 2020 Oct 9.
Low-carbohydrate ketogenic diet (LCKD), originally used as a treatment for childhood epilepsy is currently gaining acceptance as a nutritional therapy for obesity and type 2 diabetes. In addition, this diet has a positive effect on body weight, blood glucose level, glycosylated hemoglobin, plasma lipid profile, and neurological disorders. This review focuses on the therapeutic effectiveness, negative effects, and the rationale of using LCKD for the treatment of type 2 diabetes. It is shown that LCKD contributes to the reduction in the intake of insulin and oral antidiabetic drugs in patients with type 2 diabetes. Furthermore, the data presented in this review reveal the efficacy and cost-effectiveness of LCKD in the management of type 2 diabetes.
低碳水化合物生酮饮食（LCKD）最初用于治疗儿童癫痫，目前作为肥胖和 2 型糖尿病的营养治疗方法正被广泛接受。此外，这种饮食对体重、血糖水平、糖化血红蛋白、血浆脂质谱和神经紊乱有积极影响。本文主要综述了生酮饮食治疗 2 型糖尿病的疗效、不良反应和作用机制。研究表明，生酮饮食有助于减少 2 型糖尿病患者对胰岛素和口服降糖药的摄入。此外，本文综述的数据还揭示了生酮饮食在 2 型糖尿病管理中的疗效和成本效益。
