Sharp Tamsin H, McBride Nancy S, Howell Amy E, Evans C John, Jones Derek K, Perry Gavin, Dimitriadis Stavros I, Lancaster Thomas M, Zuccolo Luisa, Relton Caroline, Matthews Sarah M, Breeze Thomas, David Anthony S, Drakesmith Mark, Linden David E J, Paus Tomas, Walton Esther
MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, BS8 2BN, UK.
Cardiff University Brain Research Imaging Centre (CUBRIC), School of Psychology, Cardiff University, Cardiff, CF24 4HQ, UK.
Wellcome Open Res. 2020 Aug 28;5:203. doi: 10.12688/wellcomeopenres.16060.1. eCollection 2020.
Neuroimaging offers a valuable insight into human brain development by allowing assessment of structure, connectivity and function. Multimodal neuroimaging data have been obtained as part of three sub-studies within the Avon Longitudinal Study of Parents and Children, a prospective multigenerational pregnancy and birth cohort based in the United Kingdom. Brain imaging data were acquired when offspring were between 18 and 24 years of age, and included acquisition of structural, functional and magnetization transfer magnetic resonance, diffusion tensor, and magnetoencephalography imaging. This resource provides a unique opportunity to combine neuroimaging data with extensive phenotypic and genotypic measures from participants, their mothers, and fathers.
神经影像学通过允许对结构、连通性和功能进行评估，为人类大脑发育提供了有价值的见解。作为英国一项前瞻性多代妊娠和出生队列研究——雅芳亲子纵向研究的三个子研究的一部分，已获取了多模态神经影像学数据。脑成像数据是在后代18至24岁时采集的，包括结构、功能和磁化传递磁共振、扩散张量和脑磁图成像的采集。这一资源提供了一个独特的机会，可将神经影像学数据与来自参与者及其父母的广泛表型和基因型测量数据相结合。
