Suppr超能文献

意大利新冠疫情爆发头两周(2020年2月24日至3月8日)重症监护资源的使用情况。

Use of critical care resources during the first 2 weeks (February 24-March 8, 2020) of the Covid-19 outbreak in Italy.

作者信息

Tonetti Tommaso, Grasselli Giacomo, Zanella Alberto, Pizzilli Giacinto, Fumagalli Roberto, Piva Simone, Lorini Luca, Iotti Giorgio, Foti Giuseppe, Colombo Sergio, Vivona Luigi, Rossi Sandra, Girardis Massimo, Agnoletti Vanni, Campagna Anselmo, Gordini Giovanni, Navalesi Paolo, Boscolo Annalisa, Graziano Alessandro, Valeri Ilaria, Vianello Andrea, Cereda Danilo, Filippini Claudia, Cecconi Maurizio, Locatelli Franco, Bartoletti Michele, Giannella Maddalena, Viale Pierluigi, Antonelli Massimo, Nava Stefano, Pesenti Antonio, Ranieri V Marco

机构信息

Alma Mater Studiorum, Dipartimento Di Scienze Mediche E Chirurgiche, Anesthesia and Intensive Care Medicine, Università Di Bologna, Policlinico Di Sant'Orsola, Via Massarenti, 9 40138, Bologna, Italy.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.

出版信息

Ann Intensive Care. 2020 Oct 12;10(1):133. doi: 10.1186/s13613-020-00750-z.

Abstract

BACKGROUND

A Covid-19 outbreak developed in Lombardy, Veneto and Emilia-Romagna (Italy) at the end of February 2020. Fear of an imminent saturation of available ICU beds generated the notion that rationing of intensive care resources could have been necessary.

RESULTS

In order to evaluate the impact of Covid-19 on the ICU capacity to manage critically ill patients, we performed a retrospective analysis of the first 2 weeks of the outbreak (February 24-March 8). Data were collected from regional registries and from a case report form sent to participating sites. ICU beds increased from 1545 to 1989 (28.7%), and patients receiving respiratory support outside the ICU increased from 4 (0.6%) to 260 (37.0%). Patients receiving respiratory support outside the ICU were significantly older [65 vs. 77 years], had more cerebrovascular (5.8 vs. 13.1%) and renal (5.3 vs. 10.0%) comorbidities and less obesity (31.4 vs. 15.5%) than patients admitted to the ICU. PaO/FiO ratio, respiratory rate and arterial pH were higher [165 vs. 244; 20 vs. 24 breath/min; 7.40 vs. 7.46] and PaCO and base excess were lower [34 vs. 42 mmHg; 0.60 vs. 1.30] in patients receiving respiratory support outside the ICU than in patients admitted to the ICU, respectively.

CONCLUSIONS

Increase in ICU beds and use of out-of-ICU respiratory support allowed effective management of the first 14 days of the Covid-19 outbreak, avoiding resource rationing.

摘要

背景

2020年2月底,意大利的伦巴第、威尼托和艾米利亚-罗马涅爆发了新冠疫情。由于担心可用的重症监护病房床位即将饱和,人们认为可能有必要对重症监护资源进行配给。

结果

为了评估新冠疫情对重症监护病房管理重症患者能力的影响,我们对疫情爆发的前两周(2月24日至3月8日)进行了回顾性分析。数据从地区登记处以及发送给参与研究地点的病例报告表中收集。重症监护病房床位从1545张增加到1989张(增加了28.7%),在重症监护病房外接受呼吸支持的患者从4名(0.6%)增加到260名(37.0%)。在重症监护病房外接受呼吸支持的患者比入住重症监护病房的患者年龄显著更大(分别为65岁和77岁),有更多的脑血管疾病(分别为5.8%和13.1%)和肾脏疾病(分别为5.3%和10.0%),肥胖患者更少(分别为31.4%和15.5%)。在重症监护病房外接受呼吸支持的患者的氧合指数、呼吸频率和动脉血pH值分别比入住重症监护病房的患者更高(分别为165和244;20次/分钟和24次/分钟;7.40和7.46),而二氧化碳分压和碱剩余更低(分别为34 mmHg和42 mmHg;0.60和1.30)。

结论

增加重症监护病房床位以及采用重症监护病房外的呼吸支持,使得在新冠疫情爆发的前14天能够进行有效的管理,避免了资源配给。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a49d/7550519/a7d1a1080863/13613_2020_750_Fig1_HTML.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验