Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
J Infect Dis. 2021 Jun 4;223(11):1948-1952. doi: 10.1093/infdis/jiaa650.
Despite evidence that older children and adolescents bear the highest burden of malaria, large malaria surveys focus on younger children. We used polymerase chain reaction data from the 2013-2014 Demographic and Health Survey in the Democratic Republic of Congo (including children aged <5 years and adults aged ≥15 years) and a longitudinal study in Kinshasa Province (participants aged 6 months to 98 years) to estimate malaria prevalence across age strata. We fit linear models and estimated prevalences for each age category; adolescents aged 10-14 years had the highest prevalence. We estimate approximately 26 million polymerase chain reaction-detectable infections nationally. Adolescents and older children should be included in surveillance studies.
尽管有证据表明，年龄较大的儿童和青少年所受疟疾负担最重，但大规模疟疾调查的重点仍放在年龄较小的儿童身上。我们利用刚果民主共和国 2013-2014 年人口与健康调查中的聚合酶链反应数据（包括年龄＜5 岁的儿童和年龄≥15 岁的成年人）以及金沙萨省的一项纵向研究（年龄 6 个月至 98 岁的参与者），估计了各年龄组的疟疾流行率。我们拟合了线性模型，并估计了每个年龄组的流行率；10-14 岁的青少年发病率最高。我们估计全国约有 2600 万例聚合酶链反应检测到的感染。因此，应将青少年和较大儿童纳入监测研究中。
