作为天然产物发现资源的[相关属名]成员的基因组组装
Genomic Assemblies of Members of and Related Genera as a Resource for Natural Product Discovery.
作者信息
Mullins Alex J, Jones Cerith, Bull Matthew J, Webster Gordon, Parkhill Julian, Connor Thomas R, Murray James A H, Challis Gregory L, Mahenthiralingam Eshwar
机构信息
Microbiomes, Microbes, and Informatics Group, School of Biosciences, Cardiff University, Cardiff, United Kingdom
Microbiomes, Microbes, and Informatics Group, School of Biosciences, Cardiff University, Cardiff, United Kingdom.
出版信息
Microbiol Resour Announc. 2020 Oct 15;9(42):e00485-20. doi: 10.1128/MRA.00485-20.
Abstract
The genomes of 450 members of , isolated from clinical and environmental sources, were sequenced and assembled as a resource for genome mining. Genomic analysis of the collection has enabled the identification of multiple metabolites and their biosynthetic gene clusters, including the antibiotics gladiolin, icosalide A, enacyloxin, and cepacin A.
摘要
从临床和环境来源分离出的450个成员的基因组被测序并组装，作为基因组挖掘的资源。对该集合的基因组分析已能够鉴定多种代谢物及其生物合成基因簇，包括抗生素剑兰菌素、二十烷内酯A、恩那西毒素和洋葱菌素A。
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本文引用的文献
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