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对于出现类似新冠症状和/或有显著新冠病毒暴露史的患者，单次鼻咽部新冠病毒聚合酶链反应（PCR）拭子检测的预测价值是什么？

What Is the Predictive Value of a Single Nasopharyngeal SARS-CoV-2 PCR Swab Test in a Patient With COVID-Like Symptoms and/or Significant COVID-19 Exposure?

作者信息

George Blessen, McGee James, Giangrasso Eileen, Finkelstein Sheila, Wu Susan, Glatt Aaron E

机构信息

Mount Sinai South Nassau, Oceanside, New York, USA.

Department of Medicine, Mount Sinai South Nassau, Oceanside, New York, USA.

出版信息

Open Forum Infect Dis. 2020 Sep 1;7(10):ofaa399. doi: 10.1093/ofid/ofaa399. eCollection 2020 Oct.

DOI:10.1093/ofid/ofaa399
PMID:33062799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7499796/
Abstract

Utilizing results of polymerase chain reaction (PCR) testing and subsequent antibody titers, we report on the test characteristics of a PCR screening test for severe acute respiratory syndrome coronavirus 2 among hospital workers. The PCR test was found to be 87% sensitive and 97% specific, with a positive predictive value of 0.98 and a negative predictive value of 0.80.

摘要

利用聚合酶链反应（PCR）检测结果及后续抗体滴度，我们报告了医院工作人员中针对严重急性呼吸综合征冠状病毒2的PCR筛查检测的检测特征。发现该PCR检测的敏感性为87%，特异性为97%，阳性预测值为0.98，阴性预测值为0.80。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1163/7539688/2e5f994abd66/ofaa399_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1163/7539688/2e5f994abd66/ofaa399_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1163/7539688/2e5f994abd66/ofaa399_fig1.jpg

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