• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

抗菌聚合物在牙科树脂复合材料开发中的应用。

Application of Antimicrobial Polymers in the Development of Dental Resin Composite.

机构信息

School of Chemistry and Chemical Engineering, Shandong University of Technology, 266 Xincun Road, Zibo 255000, China.

出版信息

Molecules. 2020 Oct 15;25(20):4738. doi: 10.3390/molecules25204738.

DOI:10.3390/molecules25204738
PMID:33076515
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7587579/
Abstract

Dental resin composites have been widely used in a variety of direct and indirect dental restorations due to their aesthetic properties compared to amalgams and similar metals. Despite the fact that dental resin composites can contribute similar mechanical properties, they are more likely to have microbial accumulations leading to secondary caries. Therefore, the effective and long-lasting antimicrobial properties of dental resin composites are of great significance to their clinical applications. The approaches of ascribing antimicrobial properties to the resin composites may be divided into two types: The filler-type and the resin-type. In this review, the resin-type approaches were highlighted. Focusing on the antimicrobial polymers used in dental resin composites, their chemical structures, mechanical properties, antimicrobial effectiveness, releasing profile, and biocompatibility were included, and challenges, as well as future perspectives, were also discussed.

摘要

牙科树脂复合材料由于其美观性能,与汞合金和类似金属相比,已广泛应用于各种直接和间接的牙科修复。尽管牙科树脂复合材料可以提供相似的机械性能,但它们更容易积聚微生物,导致继发龋。因此,牙科树脂复合材料具有有效且持久的抗菌性能对其临床应用具有重要意义。赋予树脂复合材料抗菌性能的方法可分为两种类型:填料型和树脂型。本综述重点介绍了树脂型方法。关注牙科树脂复合材料中使用的抗菌聚合物,包括其化学结构、机械性能、抗菌效果、释放特性和生物相容性,并讨论了挑战和未来展望。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/9a7f6219b9ec/molecules-25-04738-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/38efd475925b/molecules-25-04738-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/19a08793c185/molecules-25-04738-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/d2dfb64610ea/molecules-25-04738-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/ba472e22eef4/molecules-25-04738-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/be2670315a46/molecules-25-04738-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/9a7f6219b9ec/molecules-25-04738-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/38efd475925b/molecules-25-04738-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/19a08793c185/molecules-25-04738-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/d2dfb64610ea/molecules-25-04738-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/ba472e22eef4/molecules-25-04738-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/be2670315a46/molecules-25-04738-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d8c/7587579/9a7f6219b9ec/molecules-25-04738-g006.jpg

相似文献

1
Application of Antimicrobial Polymers in the Development of Dental Resin Composite.抗菌聚合物在牙科树脂复合材料开发中的应用。
Molecules. 2020 Oct 15;25(20):4738. doi: 10.3390/molecules25204738.
2
Synthesis of core-shell structured ZnO@m-SiO with excellent reinforcing effect and antimicrobial activity for dental resin composites.核壳结构 ZnO@m-SiO 的合成及其在牙科树脂复合材料中的增强和抗菌性能。
Dent Mater. 2018 Dec;34(12):1846-1855. doi: 10.1016/j.dental.2018.10.002. Epub 2018 Oct 25.
3
Evaluation of the filler packing structures in dental resin composites: From theory to practice.评估牙科树脂复合材料中的填充物填充结构:从理论到实践。
Dent Mater. 2018 Jul;34(7):1014-1023. doi: 10.1016/j.dental.2018.03.022. Epub 2018 Apr 16.
4
Silver sulfadiazine immobilized glass as antimicrobial fillers for dental restorative materials.磺胺嘧啶银固定化玻璃作为牙科修复材料的抗菌填料。
Mater Sci Eng C Mater Biol Appl. 2017 Jun 1;75:524-534. doi: 10.1016/j.msec.2017.02.069. Epub 2017 Feb 17.
5
Development of mechanical properties in dental resin composite: Effect of filler size and filler aggregation state.牙科用树脂复合材料力学性能的发展:填料粒径和填料聚集状态的影响。
Mater Sci Eng C Mater Biol Appl. 2019 Aug;101:274-282. doi: 10.1016/j.msec.2019.03.090. Epub 2019 Mar 26.
6
Bioactive glass fillers reduce bacterial penetration into marginal gaps for composite restorations.生物活性玻璃填料可减少细菌渗入复合修复体的边缘间隙。
Dent Mater. 2016 Jan;32(1):73-81. doi: 10.1016/j.dental.2015.10.007. Epub 2015 Nov 24.
7
Antimicrobial and mechanical properties of dental resin composite containing bioactive glass.含生物活性玻璃的牙科树脂复合材料的抗菌及力学性能
J Appl Biomater Funct Mater. 2016 Jul 26;14(3):e296-301. doi: 10.5301/jabfm.5000271.
8
Hydrophobic and antimicrobial dentin: A peptide-based 2-tier protective system for dental resin composite restorations.疏水性和抗菌性牙本质:用于牙科树脂复合材料修复的基于肽的两级保护系统。
Acta Biomater. 2019 Apr 1;88:251-265. doi: 10.1016/j.actbio.2019.02.007. Epub 2019 Feb 10.
9
High performance dental resin composites with hydrolytically stable monomers.具有水解稳定单体的高性能牙科树脂复合材料。
Dent Mater. 2018 Feb;34(2):228-237. doi: 10.1016/j.dental.2017.10.007. Epub 2017 Nov 4.
10
Polymer grafted hydroxyapatite whisker as a filler for dental composite resin with enhanced physical and mechanical properties.聚合物接枝羟基磷灰石晶须作为增强牙科复合树脂物理和机械性能的填料。
Mater Sci Eng C Mater Biol Appl. 2013 Dec 1;33(8):4994-5000. doi: 10.1016/j.msec.2013.08.029. Epub 2013 Aug 31.

引用本文的文献

1
Resin Composites with Anti-Biofouling Zwitterionic Polymer and Silica/Zirconia Filler for Digital Light Processing (DLP) of Dental Protheses.用于牙科修复体数字光处理(DLP)的含抗生物污损两性离子聚合物和二氧化硅/氧化锆填料的树脂复合材料。
Materials (Basel). 2025 Aug 5;18(15):3677. doi: 10.3390/ma18153677.
2
A review of new generation of dental restorative resin composites with antibacterial, remineralizing and self-healing capabilities.具有抗菌、再矿化和自愈能力的新一代牙科修复树脂复合材料综述。
Discov Nano. 2024 Nov 21;19(1):189. doi: 10.1186/s11671-024-04151-0.
3
Current approaches to produce durable biomaterials: Trends in polymeric materials for restorative dentistry applications.

本文引用的文献

1
Methacrylate perspective in current dental practice.当前牙科实践中的甲基丙烯酸盐展望。
J Esthet Restor Dent. 2020 Oct;32(7):673-680. doi: 10.1111/jerd.12633. Epub 2020 Aug 3.
2
Biological Activity of Quaternary Ammonium Salts and Their Derivatives.季铵盐及其衍生物的生物活性。
Pathogens. 2020 Jun 10;9(6):459. doi: 10.3390/pathogens9060459.
3
Development of novel surface coating composed of MDPB and MPC with dual functionality of antibacterial activity and protein repellency.开发具有抗菌活性和抗蛋白质附着双重功能的新型 MDPB 和 MPC 表面涂层。
制备耐用生物材料的当前方法:用于口腔修复应用的聚合材料趋势。
Dent Mater. 2024 Dec;40(12):2122-2134. doi: 10.1016/j.dental.2024.10.004. Epub 2024 Oct 18.
4
The Effect of Incorporating Dimethylaminohexadecyl Methacrylate and/or 2-Methacryloyloxyethyl Phosphorylcholine on Flexural Strength and Surface Hardness of Heat Polymerized and 3D-Printed Denture Base Materials.甲基丙烯酸二甲氨基十六酯和/或2-甲基丙烯酰氧基乙基磷酰胆碱对热聚合和3D打印义齿基托材料弯曲强度及表面硬度的影响
Materials (Basel). 2024 Sep 20;17(18):4625. doi: 10.3390/ma17184625.
5
In vitro analysis of a novel dimethylaminododecyl methacrylate modification of dental acrylic soft liner material.一种新型二甲氨十二烷基甲基丙烯酸酯改性牙科丙烯酸软衬材料的体外分析。
Sci Rep. 2024 Aug 27;14(1):19855. doi: 10.1038/s41598-024-69836-z.
6
Modern Polymers for Dental Application.牙科应用的现代聚合物。
Biomedicines. 2024 Jan 23;12(2):252. doi: 10.3390/biomedicines12020252.
7
A Multifunctional Dental Resin Composite with Sr-N-Doped TiO and n-HA Fillers for Antibacterial and Mineralization Effects.一种具有 Sr-N 掺杂 TiO2 和 n-HA 填料的多功能牙科树脂复合材料,具有抗菌和矿化效果。
Int J Mol Sci. 2023 Jan 9;24(2):1274. doi: 10.3390/ijms24021274.
8
Adhesive Ability of Different Oral Pathogens to Various Dental Materials: An Study.不同口腔病原体对各种牙科材料的黏附能力:一项研究。
Can J Infect Dis Med Microbiol. 2022 Aug 1;2022:9595067. doi: 10.1155/2022/9595067. eCollection 2022.
9
The Current Antimicrobial and Antibiofilm Activities of Synthetic/Herbal/Biomaterials in Dental Application.口腔应用中合成/草药/生物材料的抗菌和抗生物膜活性的最新研究进展
Biomed Res Int. 2022 Aug 2;2022:8856025. doi: 10.1155/2022/8856025. eCollection 2022.
10
The Antibacterial and Remineralizing Effects of Biomaterials Combined with DMAHDM Nanocomposite: A Systematic Review.生物材料与DMAHDM纳米复合材料联合应用的抗菌及再矿化作用:一项系统评价
Materials (Basel). 2021 Mar 30;14(7):1688. doi: 10.3390/ma14071688.
J Biomed Mater Res B Appl Biomater. 2020 Nov;108(8):3241-3249. doi: 10.1002/jbm.b.34661. Epub 2020 Jun 10.
4
Quantum Dots of Tantalum Oxide with an Imidazolium Ionic Liquid as Antibacterial Agent for Adhesive Resin.氧化钽量子点与离子液体作为抗菌剂用于黏附树脂。
J Adhes Dent. 2020;22(2):207-214. doi: 10.3290/j.jad.a44285.
5
Quaternary ammonium-based biomedical materials: State-of-the-art, toxicological aspects and antimicrobial resistance.基于季铵盐的生物医学材料:最新进展、毒理学方面及抗菌耐药性。
Prog Polym Sci. 2017 Aug;71:53-90. doi: 10.1016/j.progpolymsci.2017.03.001. Epub 2017 Mar 12.
6
Antimicrobial properties of benzalkonium chloride derived polymerizable deep eutectic solvent.苄索氯铵衍生聚合型深共晶溶剂的抗菌性能。
Int J Pharm. 2020 Feb 15;575:119005. doi: 10.1016/j.ijpharm.2019.119005. Epub 2019 Dec 30.
7
In situ surface modification on dental composite resin using 2-methacryloyloxyethyl phosphorylcholine polymer for controlling plaque formation.利用 2-(甲基丙烯酰氧)乙基磷酰胆碱聚合物对牙科复合树脂进行原位表面改性,以控制菌斑形成。
Mater Sci Eng C Mater Biol Appl. 2019 Nov;104:109916. doi: 10.1016/j.msec.2019.109916. Epub 2019 Jun 25.
8
Ionic liquid as antibacterial agent for an experimental orthodontic adhesive.离子液体作为一种实验性正畸胶粘剂的抗菌剂。
Dent Mater. 2019 Aug;35(8):1155-1165. doi: 10.1016/j.dental.2019.05.010. Epub 2019 May 23.
9
Dental restorative composite materials: A review.牙科修复复合材料:综述
J Oral Biosci. 2019 Jun;61(2):78-83. doi: 10.1016/j.job.2019.04.001. Epub 2019 May 15.
10
Novel anti-biofouling light-curable fluoride varnish containing 2-methacryloyloxyethyl phosphorylcholine to prevent enamel demineralization.新型含 2-甲基丙烯酰氧乙基磷酰胆碱的光固化防污氟涂料,用于预防牙釉质脱矿。
Sci Rep. 2019 Feb 5;9(1):1432. doi: 10.1038/s41598-018-38255-2.