Matsui Mary S
Teaneck, NJ USA.
Curr Dermatol Rep. 2020;9(4):323-330. doi: 10.1007/s13671-020-00315-0. Epub 2020 Oct 14.
The goal of this review is to provide an update in the field of vitamin D, in particular, the role of vitamin D in non-skeletal health, the complexity of providing patient guidance regarding obtaining sufficient vitamin D, and the possible involvement of vitamin D in morbidity and mortality due to SARS-CoV-2 (COVID-19).
In addition to bone health, vitamin D may play a role in innate immunity, cardiovascular disease, and asthma. Although rickets is often regarded as an historical disease of the early twentieth century, it appears to be making a comeback worldwide, including "first-world" countries. Broad-spectrum sunscreens (with high UVA filters) that prevent erythema are unlikely to compromise vitamin D status in healthy populations.
New attention is now focused on the role of vitamin D in a variety of diseases, and more individualized patient recommendation schemes are being considered that take into account more realistic and achievable goals for achieving sufficient vitamin D through diet, supplements, and sun behavior.
本综述的目的是提供维生素D领域的最新进展，特别是维生素D在非骨骼健康方面的作用、为患者提供关于获取足够维生素D的指导的复杂性，以及维生素D可能与严重急性呼吸综合征冠状病毒2（COVID-19）导致的发病率和死亡率的关系。
除了骨骼健康外，维生素D可能在先天免疫、心血管疾病和哮喘中发挥作用。尽管佝偻病通常被视为20世纪初的一种历史疾病，但它似乎正在全球范围内卷土重来，包括“第一世界”国家。能预防红斑的广谱防晒霜（含高UVA滤光剂）不太可能损害健康人群的维生素D状况。
现在新的关注点集中在维生素D在多种疾病中的作用，并且正在考虑更个性化的患者推荐方案，该方案会考虑到通过饮食、补充剂和晒太阳行为来实现足够维生素D摄入的更现实且可实现的目标。
