Vigeh Mohsen, Yokoyama Kazuhito, Matsukawa Takehisa, Shinohara Atsuko, Ohtani Katsumi, Shariat Mamak
Maternal, Fetal, and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Department of Epidemiology and Environmental Health, Faculty of Medicine, Juntendo University, Tokyo, Japan.
Iran J Public Health. 2020 Aug;49(8):1510-1519. doi: 10.18502/ijph.v49i8.3895.
Exposure to toxic metals remains a public health problem with lifelong impacts on childhood growth and development. We aimed to investigate metals effects on preschool children's anthropometric variables.
The study was conducted in Tehran, Iran, from Jul 2013 to Mar 2016. We measured scalp hair metal concentrations (lead, cadmium, arsenic, zinc, manganese, and cobalt), using inductively coupled plasma mass spectrometry, in 207 preschool children's (36 to 72 months old).
A significant negative correlation between children's hair lead levels and children's weight was found (r= -0.178, ). Linear regression analysis confirmed the relationship when adjusted for the confounders, including children's age, sex, height, family income, and maternal education (β= -0.191; t= -3.426, < 0.01). The ANOVA analysis showed a significant (<0.01) difference between hair lead level and children's weight-for-age percentiles. Totally and separately, in almost all weight percentiles, hair lead levels were higher in girls than boys.
The present study on Iranian children showed the current levels of lead exposure might negatively influence on children growth, with higher risk for girls than boys.
接触有毒金属仍然是一个公共卫生问题，对儿童的生长发育具有终生影响。我们旨在调查金属对学龄前儿童人体测量学变量的影响。
该研究于2013年7月至2016年3月在伊朗德黑兰进行。我们使用电感耦合等离子体质谱法测量了207名学龄前儿童（36至72个月大）头皮头发中的金属浓度（铅、镉、砷、锌、锰和钴）。
发现儿童头发铅水平与儿童体重之间存在显著负相关（r = -0.178）。在对包括儿童年龄、性别、身高、家庭收入和母亲教育程度等混杂因素进行调整后，线性回归分析证实了这种关系（β = -0.191；t = -3.426，<0.01）。方差分析显示头发铅水平与儿童年龄别体重百分位数之间存在显著差异（<0.01）。总体而言，在几乎所有体重百分位数中，女孩的头发铅水平均高于男孩。
本项针对伊朗儿童的研究表明，目前的铅暴露水平可能会对儿童生长产生负面影响，女孩面临的风险高于男孩。
