Luo Yu-Xue, Sun Man-Lin, Shi Pei-Lei, Liu Pan, Chen Yi-Yin, Peng Xian
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Dental Basic Medicine, West China School of Stomatology, Chengdu 610041, China.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2020 Oct 1;38(5):576-582. doi: 10.7518/hxkq.2020.05.018.
Veillonella species, known as the early colonizer of oral biofilm, are prevalent in oral microbiota. Seven Veillonella species have been isolated from oral cavity. Their distribution varies not only with different people but also with different sites in the oral cavity. Oral Veillonella are associated with oral diseases. They contribute to the adhesion of Streptococcus mutans and consume the lactate generated by streptococci. Veillonella species play an important role in the occurrence and development of periodontal diseases by providing adhesion sites for Porphyromonas gingivalis and boosting immune responses. The production of lipopolysaccharide and H2S is related to other oral diseases, such as pulpitis, periapical periodontitis, and halitosis. Several studies have been conducted on the relationship between Veillonella and oral diseases and the interaction between Veillonella and other pathological microorganisms, but limited knowledge is available at the molecular level. This article reviews the research progress in the relationship between Veillonella and oral infectious diseases, such as dental caries and periodontal diseases.
韦荣氏菌属是口腔生物膜的早期定植菌，在口腔微生物群中普遍存在。已从口腔中分离出7种韦荣氏菌。它们的分布不仅因人而异，也因口腔内不同部位而异。口腔韦荣氏菌与口腔疾病有关。它们有助于变形链球菌的黏附，并消耗链球菌产生的乳酸。韦荣氏菌属通过为牙龈卟啉单胞菌提供黏附位点并增强免疫反应，在牙周疾病的发生和发展中起重要作用。脂多糖和硫化氢的产生与其他口腔疾病有关，如牙髓炎、根尖周炎和口臭。关于韦荣氏菌与口腔疾病的关系以及韦荣氏菌与其他致病微生物之间的相互作用，已经进行了多项研究，但在分子水平上的了解有限。本文综述了韦荣氏菌与龋齿和牙周疾病等口腔感染性疾病关系的研究进展。
