Clinical Pharmacy of the UHC of Nantes, and UMR INSERM 1246 SPHERE Universities of Nantes and Tours, Nantes, France.
Center for the Prevention of Infectious and Transmitted Diseases of the UHC of Nantes, Nantes, France.
PLoS One. 2020 Oct 22;15(10):e0234693. doi: 10.1371/journal.pone.0234693. eCollection 2020.
The pathogenic and oncogenic roles of papillomavirus (HPV) infections have been documented and shown to occur in women as well as in men. While other countries have already extended their vaccination guidelines to include boys, in 2019 the French National Authority for Health validated implementation of HPV vaccination in the 2020 vaccination schedule. There is, however, a climate of distrust in regard to vaccination in France, and there have been few studies to date regarding the acceptability of HPV vaccination in boys in France. The aim of this study was, therefore, to evaluate the acceptability of extending the recommendations for HPV vaccination in men, among middle and high school students and their parents.
Our study (HPVac) was a prospective, multicenter, departmental, and descriptive survey applied to a sample of male middle and high school students attending schools in the Loire-Atlantique department and their parents. It took place from January 2017 to January 2018.
We analyzed the information obtained from 127 parent questionnaires and 145 children questionnaires. In terms of acceptability, 36.6% (n = 53) of the children and 37.8% (n = 48) of the parents were in favour of being vaccinated or of having their children vaccinated against HPV (51.7% (n = 75) and 50.4% (n = 64), respectively, were undecided). The perception of a risk stemming from HPV infection was positively associated with acceptability of the HPV vaccine. Being against vaccines in general, being discouraged by their parents, parents thinking that their child is not at risk, and the belief that the vaccine is not mandatory were arguments cited and significantly associated with a willingness to be vaccinated.
This study revealed a lack of information among boys and their parents about HPV and its vaccination. It also clearly showed that taking time to discuss the consequences of an infection and the merits of being vaccinated can help parents overcome their reluctance. The children then generally go along with their parent's choice.
人乳头瘤病毒（HPV）感染的致病和致癌作用已得到证实，并已在女性和男性中发生。虽然其他国家已经扩大了疫苗接种指南，将男孩也包括在内，但在 2019 年，法国国家卫生管理局批准在 2020 年的疫苗接种计划中实施 HPV 疫苗接种。然而，法国对疫苗接种存在不信任的气氛，迄今为止，关于法国男孩 HPV 疫苗接种的可接受性的研究很少。因此，本研究旨在评估将 HPV 疫苗接种推荐范围扩大到男性中学生及其家长的可接受性。
我们的研究（HPVac）是一项前瞻性、多中心、部门和描述性调查，针对在卢瓦尔-大西洋省上学的男性中学生及其家长进行抽样调查。研究于 2017 年 1 月至 2018 年 1 月进行。
我们分析了从 127 份家长问卷和 145 份儿童问卷中获得的信息。在可接受性方面，36.6%（n = 53）的儿童和 37.8%（n = 48）的家长赞成接种或让孩子接种 HPV 疫苗（分别有 51.7%（n = 75）和 50.4%（n = 64）的家长未决定）。对 HPV 感染风险的认识与 HPV 疫苗的可接受性呈正相关。一般反对疫苗、被父母劝阻、父母认为孩子没有风险、以及认为疫苗不是强制性的，这些都是被引用并与接种意愿显著相关的论据。
这项研究表明，男孩及其家长对 HPV 及其疫苗接种的了解不足。它还清楚地表明，花时间讨论感染的后果和接种疫苗的好处，可以帮助家长克服他们的不情愿。然后，孩子们通常会听从父母的选择。
