School of Allied Health Sciences, Walailak University, Nakhonsithammarat 80160, Thailand.
School of Medicine, Walailak University, Nakhonsithammarat 80160, Thailand.
Molecules. 2020 Oct 21;25(20):4865. doi: 10.3390/molecules25204865.
Tangerine () is one of the most important crops of Thailand with a total harvest that exceeds 100,000 tons. Citrus essential oils are widely used as aromatherapy and medicinal agents. The effect of tangerine essential oil on human brain waves and sleep activity has not been reported. In the present study, we therefore evaluated these effects of tangerine essential oil by measurement of electroencephalography (EEG) activity with 32 channel platforms according to the international 10-20 system in 10 male and 10 female subjects. Then the sleep onset latency was studied to further confirm the effect on sleep activity. The results revealed that different concentrations, subthreshold to suprathreshold, of tangerine oil gave different brain responses. Undiluted tangerine oil inhalation reduced slow and fast alpha wave powers and elevated low and mid beta wave powers. The subthreshold and threshold dilution showed the opposite effect to the brain compared with suprathreshold concentration. Inhalation of threshold concentration showed effectively decreased alpha and beta wave powers and increased theta wave power, which emphasize its sedative effect. The reduction of sleep onset latency was confirmed with the implementation of the observed sedative effect of tangerine oil.
橘子（Citrus reticulata Blanco）是泰国最重要的作物之一，总收获量超过 10 万吨。柑橘精油被广泛用作芳香疗法和药用剂。然而，橘子精油对人类脑电波和睡眠活动的影响尚未有报道。因此，在本研究中，我们使用根据国际 10-20 系统的 32 通道平台，对 10 名男性和 10 名女性受试者的脑电图（EEG）活动进行了测量，评估了橘子精油的这些作用。然后，我们研究了睡眠潜伏期，以进一步证实其对睡眠活动的影响。结果表明，橘子油的不同浓度，阈下到阈上，会产生不同的大脑反应。未稀释的橘子油吸入会降低慢波和快波阿尔法波的功率，增加低波和中波贝塔波的功率。阈下和阈浓度显示出与大脑相反的效果，而超阈值浓度则相反。阈浓度的吸入有效地降低了阿尔法和贝塔波的功率，并增加了θ波的功率，这强调了其镇静作用。通过观察橘子油的镇静作用的实施，证实了睡眠潜伏期的减少。
