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白细胞介素-17A基因多态性与慢性牙周炎风险关联的Meta分析

Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis.

作者信息

Sasikumar P K, Varghese Sheeja S, Kumaran Thanga, Devi Sakthi Saranya

机构信息

Department of Periodontics, JKKN Dental College, Namakkal, Tamil Nadu, India.

Department of Periodontics, Saveetha Dental College, Chennai, Tamil Nadu, India.

出版信息

Contemp Clin Dent. 2020 Jan-Mar;11(1):3-9. doi: 10.4103/ccd.ccd_448_19. Epub 2020 Jul 13.

DOI:10.4103/ccd.ccd_448_19
PMID:33110301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7580746/
Abstract

The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis.

摘要

基因多态性与牙周炎的关联已得到广泛研究。白细胞介素-7（IL-17）是一组细胞因子，由六个不同分子（IL-17A、B、C、D、E和F）组成。其中，IL-17A是最常被了解的细胞因子，其多态性在炎症性疾病和牙周炎症中起关键作用。本研究旨在汇总可用于荟萃分析的数据，并评估IL-17A（rs2275913）多态性是否与慢性牙周炎的易感性相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/7580746/2c95f1320e69/CCD-11-3-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/7580746/0138d3cbf4ed/CCD-11-3-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/7580746/2c1224b89ea0/CCD-11-3-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/7580746/2c95f1320e69/CCD-11-3-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/7580746/0138d3cbf4ed/CCD-11-3-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/7580746/2c1224b89ea0/CCD-11-3-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce3/7580746/2c95f1320e69/CCD-11-3-g003.jpg

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Immunobiology. 2018 Apr-May;223(4-5):349-355. doi: 10.1016/j.imbio.2017.10.046. Epub 2017 Oct 27.
3
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Mol Biol Rep. 2017 Dec;44(6):443-453. doi: 10.1007/s11033-017-4128-x. Epub 2017 Oct 13.
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