Rendle Jessica, Jackson Bethany, Hoorn Stephen Vander, Yeap Lian, Warren Kristin, Donaldson Rebecca, Ward Samantha J, Vogelnest Larry, McLelland David, Lynch Michael, Vitali Simone, Sayers Ghislaine, Wyss Fabia, Webster Darren, Snipp Ross, Vaughan-Higgins Rebecca
Conservation Medicine, College of Science Health, Education and Engineering, Murdoch University, Perth 6150, Australia.
Twycross Zoo, Atherstone, Warwickshire CV9 3PX, UK.
Animals (Basel). 2020 Oct 23;10(11):1954. doi: 10.3390/ani10111954.
Macropod Progressive Periodontal Disease (MPPD) is a well-recognised disease that causes high morbidity and mortality in captive macropods worldwide. Epidemiological data on MMPD are limited, although multiple risk factors associated with a captive environment appear to contribute to the development of clinical disease. The identification of risk factors associated with MPPD would assist with the development of preventive management strategies, potentially reducing mortality. Veterinary and husbandry records from eight institutions across Australia and Europe were analysed in a retrospective cohort study (1995 to 2016), examining risk factors for the development of MPPD. A review of records for 2759 macropods found incidence rates (IR) and risk of infection differed between geographic regions and individual institutions. The risk of developing MPPD increased with age, particularly for macropods >10 years (Australia Incidence Rate Ratio (IRR) 7.63, < 0.001; Europe IRR 7.38, < 0.001). Prognosis was typically poor, with 62.5% mortality reported for Australian and European regions combined. Practical recommendations to reduce disease risk have been developed, which will assist zoos in providing optimal long-term health management for captive macropods and, subsequently, have a positive impact on both the welfare and conservation of macropods housed in zoos globally.
袋鼠进行性牙周病（MPPD）是一种广为人知的疾病，在全球圈养袋鼠中导致高发病率和死亡率。关于MPPD的流行病学数据有限，尽管与圈养环境相关的多种风险因素似乎促成了临床疾病的发展。识别与MPPD相关的风险因素将有助于制定预防管理策略，可能降低死亡率。在一项回顾性队列研究（1995年至2016年）中，分析了来自澳大利亚和欧洲八个机构的兽医和饲养记录，以研究MPPD发生的风险因素。对2759只袋鼠的记录进行审查发现，发病率（IR）和感染风险在不同地理区域和各个机构之间存在差异。患MPPD的风险随年龄增加而增加，尤其是对于年龄大于10岁的袋鼠（澳大利亚发病率比（IRR）为7.63，<0.001；欧洲IRR为7.38，<0.001）。总体预后通常较差，澳大利亚和欧洲地区合并报告的死亡率为62.5%。已制定了降低疾病风险的实用建议，这将有助于动物园为圈养袋鼠提供最佳的长期健康管理，进而对全球动物园中袋鼠的福利和保护产生积极影响。
