• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Immune Tolerance as the Physiologic Counterpart of Chronic Inflammation.

作者信息

Rogovskii Vladimir

机构信息

Department of Molecular Pharmacology and Radiobiology, Pirogov Russian National Research Medical University, Moscow, Russia.

Department of Neuroimmunology, Federal Center of Brain Research and Neurotechnologies, Moscow, Russia.

出版信息

Front Immunol. 2020 Sep 30;11:2061. doi: 10.3389/fimmu.2020.02061. eCollection 2020.

DOI:10.3389/fimmu.2020.02061
PMID:33117330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7561427/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2016/7561427/a23bae51387c/fimmu-11-02061-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2016/7561427/a23bae51387c/fimmu-11-02061-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2016/7561427/a23bae51387c/fimmu-11-02061-g0001.jpg

相似文献

1
Immune Tolerance as the Physiologic Counterpart of Chronic Inflammation.免疫耐受作为慢性炎症的生理对应物。
Front Immunol. 2020 Sep 30;11:2061. doi: 10.3389/fimmu.2020.02061. eCollection 2020.
2
Unresolved inflammation: 'immune tsunami' or erosion of integrity in immune-privileged and immune-responsive tissues and acute and chronic inflammatory diseases or cancer.未解决的炎症：“免疫海啸”还是免疫特权和免疫反应组织以及急性和慢性炎症性疾病或癌症的完整性被破坏？
Expert Opin Biol Ther. 2011 Nov;11(11):1419-32. doi: 10.1517/14712598.2011.592826. Epub 2011 Jun 11.
3
Immunology of aging and cancer development.衰老与癌症发展的免疫学
Interdiscip Top Gerontol. 2013;38:38-48. doi: 10.1159/000343599. Epub 2013 Jan 17.
4
Age-related changes in ocular mucosal tolerance: Lessons learned from gut and respiratory tract immunity.年龄相关的眼黏膜耐受性变化：从肠道和呼吸道免疫中得到的启示。
Immunology. 2021 Sep;164(1):43-56. doi: 10.1111/imm.13338. Epub 2021 May 2.
5
[Chronic inflammation and organismal aging].[慢性炎症与机体衰老]
Clin Calcium. 2013 Jan;23(1):51-8.
6
The Linkage Between Inflammation and Immune Tolerance: Interfering with Inflammation in Cancer.炎症与免疫耐受之间的联系：癌症中对炎症的干预
Curr Cancer Drug Targets. 2017;17(4):325-332. doi: 10.2174/1568009617666170109110816.
7
Biology of dendritic cells in aging.衰老过程中树突状细胞的生物学特性
J Clin Immunol. 2008 Jan;28(1):14-20. doi: 10.1007/s10875-007-9127-6. Epub 2007 Sep 9.
8
When Clarity Is Crucial: Regulating Ocular Surface Immunity.当清晰至关重要时：调节眼表面免疫。
Trends Immunol. 2018 Apr;39(4):288-301. doi: 10.1016/j.it.2017.11.007. Epub 2017 Dec 14.
9
Editorial: Cytokines in inflammation, aging, cancer and obesity.
Cytokine. 2016 Jun;82:1-3. doi: 10.1016/j.cyto.2016.03.011. Epub 2016 Mar 17.
10
Aging, inflammation, immunity and periodontal disease.衰老、炎症、免疫与牙周病。
Periodontol 2000. 2016 Oct;72(1):54-75. doi: 10.1111/prd.12135.

引用本文的文献

1
Association between neutrophil-lymphocyte ratio and female breast cancer: an observational study from NHANES 2001-2018 with external validation.中性粒细胞与淋巴细胞比值和女性乳腺癌之间的关联：一项基于2001 - 2018年美国国家健康与营养检查调查（NHANES）的观察性研究及外部验证
Front Oncol. 2025 Jul 8;15:1564238. doi: 10.3389/fonc.2025.1564238. eCollection 2025.
2
Pre-Existing Diabetes Alters Pulmonary Inflammatory Gene Expression Priming for Injury.既往糖尿病会改变肺部炎症基因表达，引发损伤。
FASEB J. 2025 Jul 31;39(14):e70804. doi: 10.1096/fj.202500816R.
3
Investigating the association between polyunsaturated fatty acids and osteomyelitis by Mendelian randomization.

本文引用的文献

1
Modulation of Inflammation-Induced Tolerance in Cancer.癌症中炎症诱导耐受性的调节
Front Immunol. 2020 Jun 26;11:1180. doi: 10.3389/fimmu.2020.01180. eCollection 2020.
2
NOD2 modulates immune tolerance via the GM-CSF-dependent generation of CD103 dendritic cells.NOD2 通过 GM-CSF 依赖性的 CD103 树突状细胞生成来调节免疫耐受。
Proc Natl Acad Sci U S A. 2020 May 19;117(20):10946-10957. doi: 10.1073/pnas.1912866117. Epub 2020 Apr 29.
3
Pharmacologic Induction of Endotoxin Tolerance in Dendritic Cells by L-Kynurenine.
通过孟德尔随机化研究多不饱和脂肪酸与骨髓炎之间的关联。
Sci Rep. 2025 Apr 28;15(1):14760. doi: 10.1038/s41598-025-98502-1.
4
Evaluating the safety, pharmacokinetics and efficacy of phage therapy in treating fracture-related infections with multidrug-resistant : intravenous versus local application in sheep.评估噬菌体疗法治疗耐多药骨折相关感染的安全性、药代动力学和疗效：绵羊静脉注射与局部应用对比
Front Cell Infect Microbiol. 2025 Apr 4;15:1547250. doi: 10.3389/fcimb.2025.1547250. eCollection 2025.
5
Multi-omics integration and immune profiling identify possible causal networks leading to uterine microbiome dysbiosis in dairy cows that develop metritis.多组学整合与免疫分析确定了导致患子宫炎的奶牛子宫微生物群失调的潜在因果网络。
Anim Microbiome. 2025 Jan 9;7(1):4. doi: 10.1186/s42523-024-00366-9.
6
Dendritic cells under the control of the preimplantation embryo secretome: an in vitro study.着床前胚胎分泌组控制下的树突状细胞：一项体外研究。
Reprod Biol Endocrinol. 2024 Nov 23;22(1):150. doi: 10.1186/s12958-024-01319-2.
7
Macrophage variants in laboratory research: most are well done, but some are RAW.实验室研究中的巨噬细胞亚型：多数做得很好，但有些还很原始。
Front Cell Infect Microbiol. 2024 Oct 9;14:1457323. doi: 10.3389/fcimb.2024.1457323. eCollection 2024.
8
Comparison of B-Cell Lupus and Lymphoma Using a Novel Immune Imbalance Transcriptomics Algorithm Reveals Potential Therapeutic Targets.使用新型免疫失衡转录组学算法比较 B 细胞狼疮和淋巴瘤，揭示潜在的治疗靶点。
Genes (Basel). 2024 Sep 17;15(9):1215. doi: 10.3390/genes15091215.
9
Tumor-produced immune regulatory factors as a therapeutic target in cancer treatment.肿瘤产生的免疫调节因子作为癌症治疗的一个治疗靶点。
Front Immunol. 2024 Aug 14;15:1416458. doi: 10.3389/fimmu.2024.1416458. eCollection 2024.
10
Molecular Mechanisms of , LGG Probiotic Function.低聚半乳糖益生菌功能的分子机制
Microorganisms. 2024 Apr 14;12(4):794. doi: 10.3390/microorganisms12040794.
L-犬尿氨酸诱导树突状细胞内毒素耐受的药理学研究。
Front Immunol. 2020 Mar 11;11:292. doi: 10.3389/fimmu.2020.00292. eCollection 2020.
4
Novel Resolution Mediators of Severe Systemic Inflammation.严重全身炎症的新型消退介质
Immunotargets Ther. 2020 Mar 6;9:31-41. doi: 10.2147/ITT.S243238. eCollection 2020.
5
Prednisolone in early pregnancy inhibits regulatory T cell generation and alters fetal and placental development in mice.孕早期使用泼尼松龙会抑制调节性 T 细胞的生成，并改变小鼠的胎儿和胎盘发育。
Mol Hum Reprod. 2020 May 15;26(5):340-352. doi: 10.1093/molehr/gaaa019.
6
Controversial Contribution of Th17/IL-17 Toward the Immune Response in Intestinal Fibrosis.Th17/IL-17 在肠道纤维化中的免疫反应中的有争议的贡献。
Dig Dis Sci. 2020 May;65(5):1299-1306. doi: 10.1007/s10620-020-06161-1.
7
Interleukin-6 signaling requires only few IL-6 molecules: Relation to physiological concentrations of extracellular IL-6.白细胞介素-6 信号仅需少量白细胞介素-6 分子：与细胞外白细胞介素-6 的生理浓度有关。
Immun Inflamm Dis. 2020 Jun;8(2):170-180. doi: 10.1002/iid3.292. Epub 2020 Feb 27.
8
T Helper Cells: The Modulators of Inflammation in Multiple Sclerosis.辅助性 T 细胞：多发性硬化症中炎症的调节者。
Cells. 2020 Feb 19;9(2):482. doi: 10.3390/cells9020482.
9
A new role for an old cytokine: GM-CSF amplifies GVHD.一种旧细胞因子的新作用：GM-CSF 扩增 GVHD。
Blood. 2020 Feb 20;135(8):520-521. doi: 10.1182/blood.2019004681.
10
Gut macrophages: key players in intestinal immunity and tissue physiology.肠道巨噬细胞：肠道免疫和组织生理学的关键参与者。
Curr Opin Immunol. 2020 Feb;62:54-61. doi: 10.1016/j.coi.2019.11.011. Epub 2019 Dec 13.