Department of Preventive Medicine, Korea University School of Medicine, Seoul, Korea.
Department of Preventive Medicine, School of Medicine, Ajou University, Suwon, Gyeonggi-do, Korea.
PLoS One. 2020 Oct 29;15(10):e0241360. doi: 10.1371/journal.pone.0241360. eCollection 2020.
The purpose of this study was to investigate the association between grip strength and hypertension in the Korean population aged 65 years or older. Furthermore, individual differences in BMI were taken into account to examine whether grip strength or a relative grip strength predicted hypertension better.
Data from the Korean Longitudinal Study of Ageing from 2006 to 2016 were assessed, and a total of 3,383 participants were analyzed in our study (Male: 1,527, Female: 1,856). Using the generalized estimating equation model, the association between grip strength and hypertension, assessed by the response to the question 'have you ever been diagnosed with hypertension from your doctor?', over the follow-up period was analyzed. The relative grip strength, calculated by dividing the mean grip strength by BMI, was also analyzed in association of hypertension.
Both grip strength and relative grip strength were significantly associated with hypertension in our sample. However, the results were more significant in the total sample when relative grip strength was used. In terms of grip strength, as the High group as reference: Low (Odds Ratio (OR): 1.238, 95% Confidence Interval (CI): 1.096, 1.397), Middle Low (OR: 1.104, 95% CI: 0.990, 1.231), and Middle high (OR: 1.024, 95% CI: 0.934, 1.122). In the analysis using relative grip strength, as High group as reference: Low (OR: 1.393, 95% CI: 1.234, 1.573), Middle low (OR: 1.232, 95% CI: 1.104, 1.374), and Middle high (OR:1.104, 95% CI: 1.009, 1.209). Furthermore, the lower QIC measure in the model with relative grip strength (QIC: 25,251) compared with the one using grip strength (QIC: 25,266) indicated a better model fit in the former.
The results of the current study strengthen the previous findings in regards to hand grip strength and health. Furthermore, the results of our study shines light on the necessity of considering individual differences in BMI, when using a physical measure as a study variable.
本研究旨在探讨韩国 65 岁及以上人群握力与高血压之间的关系。此外，还考虑了 BMI 的个体差异，以检验握力或相对握力是否能更好地预测高血压。
本研究使用了 2006 年至 2016 年韩国老龄化纵向研究的数据，共分析了 3383 名参与者（男性 1527 名，女性 1856 名）。使用广义估计方程模型，分析了随访期间握力（通过回答“医生是否曾诊断过你患有高血压？”来评估）与高血压之间的关系。还分析了用平均握力除以 BMI 计算得出的相对握力与高血压之间的关系。
在我们的样本中，握力和相对握力均与高血压显著相关。然而，当使用相对握力时，总样本的结果更为显著。就握力而言，以高组为参照：低（比值比（OR）：1.238，95%置信区间（CI）：1.096，1.397），中低（OR：1.104，95%CI：0.990，1.231），中和高（OR：1.024，95%CI：0.934，1.122）。在使用相对握力的分析中，以高组为参照：低（OR：1.393，95%CI：1.234，1.573），中低（OR：1.232，95%CI：1.104，1.374），中和高（OR：1.104，95%CI：1.009，1.209）。此外，与使用握力的模型相比（QIC：25266），使用相对握力的模型的 QIC 测量值（QIC：25251）更低，表明前者的模型拟合更好。
本研究的结果加强了之前关于手部握力与健康之间关系的研究结果。此外，本研究的结果还表明，在使用身体测量作为研究变量时，需要考虑 BMI 的个体差异。
