Kuźma Łukasz, Dąbrowski Emil Julian, Kurasz Anna, Bachórzewska-Gajewska Hanna, Dobrzycki Sławomir
Department of Invasive Cardiology, Medical University of Bialystok, 24A Sklodowskiej-Curie St, 15-276 Bialystok, Poland.
Department of Clinical Medicine, Medical University of Bialystok, 24A Sklodowskiej-Curie St, 15-276 Bialystok, Poland.
J Clin Med. 2020 Oct 27;9(11):3445. doi: 10.3390/jcm9113445.
The detrimental influence of air pollution on mortality has been established in a series of studies. The majority of them were conducted in large, highly polluted cities-there is a lack of studies from small, relatively clean regions. The aim was to analyze the short-term impact of particulate matters (PMs) on mortality in north-eastern Poland. Time-stratified case-crossover design was performed for mortality in years 2008-2017. Daily concentrations of PM (28.4 µg/m, interquartile range (IQR) = 25.2) vs. (12.6 µg/m, IQR = 9.0) and PM (29.0 µg/m, IQR = 18.0) vs. (21.7 µg/m, IQR = 14.5) were higher in Łomża than Suwałki ( < 0.001). Impact of PM on mortality was recorded in Łomża (odds ratio (OR) for IQR increase 1.061, 1.017-1.105, = 0.06, lag 0) and Suwałki (OR for IQR increase 1.044, 1.001-1.089, = 0.004, lag 0). PM had an impact on mortality in Łomża (OR for IQR increase 1.028, 1.000-1.058, = 0.049, lag 1). Cardiovascular mortality was affected by increase of PM in Łomża (1.086, 1.020-1.156, = 0.01) and Suwałki (1.085, 1.005-1.171, = 0.04). PM had an influence on respiratory mortality in Łomża (1.163, 1.021-1.380, = 0.03, lag 1). In the whole studied region, despite differences in the air quality, the influence of PMs on mortality was observed.
一系列研究证实了空气污染对死亡率的不利影响。其中大多数研究是在污染严重的大城市进行的，缺乏来自相对清洁的小区域的研究。目的是分析波兰东北部颗粒物（PM）对死亡率的短期影响。对2008 - 2017年的死亡率进行了时间分层病例交叉设计。罗兹瓦的每日PM浓度（28.4µg/m，四分位间距（IQR）= 25.2）与（12.6µg/m，IQR = 9.0）以及PM浓度（29.0µg/m，IQR = 18.0）与（21.7µg/m，IQR = 14.5）均高于苏瓦乌基（<0.001）。在罗兹瓦记录到PM对死亡率的影响（IQR增加的优势比（OR）为1.061，1.017 - 1.105，P = 0.06，滞后0）以及在苏瓦乌基（IQR增加的OR为1.044，1.001 - 1.089，P = 0.004，滞后0）。PM对罗兹瓦的死亡率有影响（IQR增加的OR为1.028，1.000 - 1.058，P = 0.049，滞后1）。罗兹瓦（1.086，1.020 - 1.156，P = 0.01）和苏瓦乌基（1.085，1.005 - 1.171，P = 0.04）的心血管死亡率受PM增加的影响。PM对罗兹瓦的呼吸道死亡率有影响（1.163，1.021 - 1.380，P = 0.03，滞后1）。在整个研究区域，尽管空气质量存在差异，但仍观察到PM对死亡率的影响。
