Integrated Brain Health Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, USA.
Frontotemporal Disorders Unit, Departments of Neurology and Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, USA.
Gerontologist. 2022 Feb 9;62(2):e123-e139. doi: 10.1093/geront/gnaa169.
The common and unique psychosocial stressors and adaptive coping strategies of people with young-onset dementia (PWDs) and their caregivers (CGs) are poorly understood. This meta-synthesis used the stress and coping framework to integrate and organize qualitative data on the common and unique psychosocial stressors and adaptive coping strategies employed by PWDs and CGs after a diagnosis of young-onset dementia (YOD).
Five electronic databases were searched for qualitative articles from inception to January 2020. Qualitative data were extracted from included articles and synthesized across articles using taxonomic analysis.
A total of 486 articles were obtained through the database and hand searches, and 322 articles were screened after the removal of duplicates. Sixty studies met eligibility criteria and are included in this meta-synthesis. Four themes emerged through meta-synthesis: (a) common psychosocial stressors experienced by both PWDs and CGs, (b) unique psychosocial stressors experienced by either PWDs or CGs, (c) common adaptive coping strategies employed by both PWDs and CGs, and (d) unique adaptive coping strategies employed by either PWDs or CGs. Within each meta-synthesis theme, subthemes pertaining to PWDs, CGs, and dyads (i.e., PWD and CG as a unit) emerged.
The majority of stressors and adaptive coping strategies of PWDs and CGs were common, supporting the use of dyadic frameworks to understand the YOD experience. Findings directly inform the development of resiliency skills interventions to promote adaptive coping in the face of a YOD diagnosis for both PWDs and CGs.
人们对早发性痴呆（PWD）患者及其照顾者（CG）的常见和独特的心理社会压力源以及适应性应对策略知之甚少。本荟萃分析使用压力和应对框架，综合和组织了 PWD 和 CG 在诊断为早发性痴呆（YOD）后的常见和独特的心理社会压力源和适应性应对策略的定性数据。
从开始到 2020 年 1 月，在五个电子数据库中搜索定性文章。从纳入的文章中提取定性数据，并使用分类分析对文章进行综合。
通过数据库和手工搜索共获得 486 篇文章，去除重复后筛选出 322 篇文章。符合纳入标准的 60 项研究被纳入此荟萃分析。通过荟萃分析得出 4 个主题：（a）PWD 和 CG 共同经历的常见心理社会压力源；（b）PWD 或 CG 经历的独特心理社会压力源；（c）PWD 和 CG 共同采用的常见适应性应对策略；（d）PWD 或 CG 采用的独特适应性应对策略。在每个荟萃分析主题中，都出现了与 PWD、CG 和对偶体（即 PWD 和 CG 作为一个单位）相关的亚主题。
PWD 和 CG 的大多数压力源和适应性应对策略都是共同的，支持使用对偶框架来理解 YOD 体验。研究结果直接为制定弹性技能干预措施提供了信息，以促进 PWD 和 CG 在面对 YOD 诊断时的适应性应对。
