Department of Pulmonology, University of Health Sciences, Ataturk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara, Turkey.
Department of Anesthesiology, University of Health Sciences, Ataturk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara, Turkey.
Aging Clin Exp Res. 2021 Mar;33(3):611-617. doi: 10.1007/s40520-020-01740-8. Epub 2020 Nov 1.
There are several screening tools used in the detection of malnutrition to facilitate nutritional support and predict prognosis in the elderly.
We aimed to compare the prognostic predictive value of geriatric nutritional risk index (GNRI) with other nutritional indices on 1 month survival in geriatric patients hospitalized for respiratory failure in intensive care unit (ICU).
A total of 191 geriatric patients (> 65 years) admitted to a specialized chest hospital with respiratory failure between January 2018 and January 2019 were analyzed. Patients were classified into two category according to 30-day survival: Survivors and Non-survivors. Nutritional assesment was done via GNRI, OPNI, NRS 2002, Nutric Scores in ICU.
Using GNRI, 146 (76.3%) geriatric patients found to be at risk of malnutrition (GNRI score: ≤ 92). GNRI < 86.9 showed significantly higher 30-day mortality rate and patients with malnutrition risk were older, had significantly lower BMI, OPNI, and higher SOFA score. The Age, NRS 2002, Nutric and SOFA score had negative correlation with GNRI. Nutric score, prealbumin and GNRI were detected as significant independent risk factors of 30-day mortality. GNRI had higher sensitivity (76.7%) but lower specificity (57.1%) compared to Nutric score and OPNI for the prediction of 30-day hospital mortality.
Compared to others, Geriatric Nutritional Risk Index (GNRI) seems to be a good predictor of 30-day mortality and having a score of less than 86.9 increase the malnutrition risk in geriatric patients hospitalized for respiratory failure in ICU.
有几种筛选工具用于检测营养不良,以方便在老年人中提供营养支持和预测预后。
我们旨在比较老年营养风险指数(GNRI)与其他营养指数对重症监护病房(ICU)因呼吸衰竭住院的老年患者 1 个月生存率的预后预测价值。
共分析了 191 名 2018 年 1 月至 2019 年 1 月因呼吸衰竭入住专门胸部医院的老年患者(>65 岁)。根据 30 天生存率将患者分为两组:存活组和非存活组。通过 GNRI、OPNI、NRS 2002、ICU 营养评分进行营养评估。
使用 GNRI,发现 146 名(76.3%)老年患者有营养不良风险(GNRI 评分:≤92)。GNRI<86.9 显示出显著更高的 30 天死亡率,且营养不良风险患者年龄较大,BMI、OPNI 较低,SOFA 评分较高。年龄、NRS 2002、Nutric 和 SOFA 评分与 GNRI 呈负相关。Nutric 评分、前白蛋白和 GNRI 被检测为 30 天死亡率的独立危险因素。与 Nutric 评分和 OPNI 相比,GNRI 对 30 天住院死亡率的预测具有更高的敏感性(76.7%)但更低的特异性(57.1%)。
与其他指标相比,老年营养风险指数(GNRI)似乎是 30 天死亡率的良好预测指标,评分低于 86.9 会增加 ICU 因呼吸衰竭住院的老年患者的营养不良风险。