Pasławska Urszula, Szczepankiewicz Barbara, Bednarska Aleksandra, Pasławski Robert
Institute of Veterinary Medicine, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University in Torun, ul. Gagarina 7, 87-100 Torun, Poland.
Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Pl. Grunwaldzki 47, 50-375 Wroclaw, Poland.
Animals (Basel). 2020 Oct 29;10(11):1988. doi: 10.3390/ani10111988.
The literature suggests that strenuous exercise and exposure to high temperatures may cause physiologic proteinuria, but to our knowledge there have been no studies that have assessed the effect of high temperatures on the occurrence of post-exercise albuminuria in dogs. The goal of the study was to assess the impact of high temperatures on the occurrence of albuminuria. Thirteen healthy adult dogs-eight female (62%) and five male (38%) had to run 5 km at a temperature of 25 °C in grasslands which took about 30-40 min. Dogs underwent clinical examinations: echocardiography, abdominal ultrasound, blood hematology and biochemistry and urinalysis, including the ratio of albumin to creatinine (UAC). Baseline UAC was on the borderline of statistical significance for female dogs, but not for male dogs, before and after exercise. UAC was 0.31 ± 0.56 mg/mmol for female dogs and 0.36 ± 0.60 mg/mmol in male dogs before exercise. Immediately after exercise, UAC was 0.51 ± 0.58 mg/mmol in female dogs and 0.31 ± 0.40 mg/mmol in male dogs. Thus, a period of about 30-40 min of intensive exercise at high temperatures (25 °C) did not lead to increased albuminuria. This suggests that there is no need to limit the movement activity before urine tests in dogs, even at high temperatures, before urinalysis.
文献表明，剧烈运动和暴露于高温环境可能会导致生理性蛋白尿，但据我们所知，尚无研究评估高温对犬类运动后蛋白尿发生情况的影响。本研究的目的是评估高温对蛋白尿发生情况的影响。13只健康成年犬——8只雌性（62%）和5只雄性（38%），必须在25°C的温度下在草原上跑5公里，这大约需要30 - 40分钟。犬只接受了临床检查：超声心动图、腹部超声、血液血液学和生物化学以及尿液分析，包括白蛋白与肌酐比值（UAC）。在运动前后，雌性犬的基线UAC处于统计学意义的临界值，但雄性犬则未达到。运动前，雌性犬的UAC为0.31±0.56mg/mmol，雄性犬为0.36±0.60mg/mmol。运动后立即测量，雌性犬的UAC为0.51±0.58mg/mmol，雄性犬为0.31±0.40mg/mmol。因此，在高温（25°C）下进行约30 - 40分钟的剧烈运动并未导致蛋白尿增加。这表明，即使在高温环境下进行尿液分析之前，犬类在尿液检测前也无需限制运动活动。
