Helse Bergen HF, Department of Urology, Haukeland University Hospital, Bergen, Norway.
Department of Clinical Medicine (K1), University of Bergen, Bergen, Norway.
J Endourol. 2021 Jul;35(7):961-966. doi: 10.1089/end.2020.0933. Epub 2021 Jan 12.
No consensus exists on how stone-free rates (SFRs) should be reported after stone treatment. The aim of this study was to assess how accurate urologists predict their patients being stone free after completing ureteroscopy (URS) and to see how various treatment strategies influenced the precision of these predictions. We also wanted to study how different definitions of stone-free status (SFS) affected the results and propose a standard definition of "stone free" to be used in future studies. A retrospective evaluation of 1019 URS done for stone treatment at Haukeland University Hospital between 2013 and 2018 was performed. Data on pretreatment status, the surgical procedure, and follow-up were recorded. SFS was defined as either no fragments detected on computed tomography (CT) after 3 months or as practical stone-free status, which also included those with small residual fragments not needing further treatment. Exact chi-squared and independent-samples -tests were used comparing data between different treatment modalities. The overall SFR, irrespective of treatment strategy and location of stone, using the no residual fragments and practical stone-free definitions were 54.2% and 74.7%, respectively. Urologists predicted intraoperatively that 91.0% of their patients treated with fragmentation and extraction would be stone free compared to 76.8% of patients treated with dusting, < 0.0001. At follow-up, the actual SFRs with no residual fragments for the two treatment strategies were 68.0% and 35.5%, respectively, < 0.0001. The practical SFRs for fragmentation and retrieval were 83.1% and 64.8% for dusting, < 0.0001. The different definitions of SFS have great impact on SFRs. Urologists are far too optimistic predicting their patient being stone free after URS. SFS should be defined as no fragments detected on CT 3 months after the URS procedure when presented in studies.
目前,针对经输尿管镜碎石取石术(ureteroscopy,URS)治疗后,无结石率(stone-free rate,SFR)应如何报告,尚未达成共识。本研究旨在评估泌尿科医生预测患者经 URS 治疗后结石清除状态的准确性,并观察不同的治疗策略如何影响这些预测的准确性。我们还希望研究不同的无结石状态(stone-free status,SFS)定义如何影响结果,并提出一个标准的“无结石”定义,以便在未来的研究中使用。
回顾性分析了 2013 年至 2018 年在豪克兰大学医院接受 URS 治疗的 1019 例结石患者的数据。记录了术前状态、手术过程和随访数据。SFS 的定义为 3 个月后 CT 无残留结石碎片或实用无结石状态,后者还包括需要进一步治疗的小残留结石碎片。使用确切的卡方检验和独立样本 t 检验比较不同治疗方法之间的数据。
无论治疗策略和结石位置如何,使用无残留碎片和实用无结石定义,总体 SFR 分别为 54.2%和 74.7%。与接受碎石和提取治疗的患者相比,泌尿科医生术中预测接受碎石术治疗的患者中有 91.0%将达到无结石状态,而接受粉尘化治疗的患者则为 76.8%, < 0.0001。在随访时,两种治疗策略的无残留碎片实际 SFR 分别为 68.0%和 35.5%, < 0.0001。对于碎石和取石,SFS 的实用定义分别为粉尘化治疗的 83.1%和 64.8%, < 0.0001。SFS 的不同定义对 SFR 有很大影响。泌尿科医生预测患者经 URS 治疗后无结石状态时过于乐观。当在研究中报告时,SFS 应定义为 URS 术后 3 个月 CT 上未检测到结石碎片。