Acta Reumatol Port. 2020 Jul-Sep;45(3):183-190.
Erasmus syndrome (ErS) is a rare entity in which Systemic Sclerosis (SSc) develops following exposure to silica, with or without associated silicosis. The objectives of this study were: 1) to evaluate the prevalence of ErS in our SSc cohort; 2) to characterize the cases; 3) to evaluate the clinical and laboratory characteristics of SSc in patients with (Ers) or without silica exposure.
Cross-sectional and analytical study. Sociodemographic, clinical and laboratory data were collected from all patients with SSc diagnosed in our department according to ACR / EULAR criteria. Data on professional activity and possible exposure to silica were obtained by phone interview.
Among 48 patients with SSc, the prevalence of ErS was 16.7% (8/48). All cases identified were male, corresponding to 72.7% of men with SSc followed at our department. There was a statistically significant association between ErS and male gender (p.
Erasmus 综合征（ErS）是一种罕见的疾病，其特征为系统性硬化症（SSc）在接触二氧化硅后发生，无论是否伴有矽肺。本研究的目的是：1）评估我们的 SSc 队列中 ErS 的患病率；2）对病例进行特征描述；3）评估有（或无）二氧化硅暴露的 ErS 患者的 SSc 临床和实验室特征。
横断面和分析性研究。从我们部门根据 ACR / EULAR 标准诊断的所有 SSc 患者中收集了社会人口统计学、临床和实验室数据。通过电话访谈获得有关职业活动和可能接触二氧化硅的信息。
在 48 名 SSc 患者中，ErS 的患病率为 16.7%（8/48）。所有确定的病例均为男性，占我们部门随访的男性 SSc 患者的 72.7%。ErS 与男性性别之间存在统计学显著关联（p
