Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Dental Materials and Biomaterial Research, Department of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Aßmannshauser Str. 4-6, 14197 Berlin, Germany.
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Dental Materials and Biomaterial Research, Department of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Aßmannshauser Str. 4-6, 14197 Berlin, Germany.
Dent Mater. 2021 Jan;37(1):e15-e22. doi: 10.1016/j.dental.2020.09.020. Epub 2020 Nov 2.
Plasma treatment can be used as surface treatment of PEEK (poly-ether-ether-ketone) to increase the bonding strength between veneering composite and dental prosthetic frameworks of PEEK or enhance biocompatibility of PEEK implants. These improvements are probably based on chemical changes of the PEEK surface. However, the aim of the study was to evaluate the impact of different low-pressure plasma treatments on surface properties of PEEK, such as roughness, hydrophilicity, micro-hardness, crystallinity and biological activity of PEEK.
Due to different plasma treatments, 143 disc-shaped specimens of pure implantable PEEK were divided into 4 groups: PEEK (no plasma treatment, n = 29), H-PEEK (hydrogen plasma treatment, n = 38), O-PEEK (oxygen plasma treatment, n = 38), H/O-PEEK (hydrogen/oxygen plasma treatment with a gas mix ratio of 2:1, n = 38). Subsequently, surface roughness, surface contact angle, surface crystallinity, surface micro-hardness and human osteoblast cell coverage area of each group were examined.
The hydrophilicity, crystallinity and micro-hardness of the plasma-treated groups increased significantly compared to the untreated group, whereas significant differences in the results of the micro-hardness tests could be shown between all groups up to a test force of 0.02N. Cell density was significantly higher on treated vs. untreated PEEK surfaces. Oxygen and H/O plasma treatments revealed to be most effective, whereas H/O plasma worked ten times faster to achieve the same effects.
The hydrogen-oxygen, 2/1-mixed plasma treatment combines the effect of hydrogen and oxygen plasma which strongly improve the surface properties of PEEK implant material, such as hydrophilicity, crystallinity, surface micro-hardness and HOB cell adhesion.
等离子体处理可用于聚醚醚酮（PEEK）的表面处理，以提高复合树脂与 PEEK 牙修复体之间的结合强度，或增强 PEEK 植入物的生物相容性。这些改善可能基于 PEEK 表面的化学变化。然而，本研究的目的是评估不同低压等离子体处理对 PEEK 表面性能的影响，如 PEEK 的粗糙度、亲水性、显微硬度、结晶度和生物活性。
由于等离子体处理方式不同，将 143 个纯植入式 PEEK 圆盘状试件分为 4 组：PEEK（无等离子体处理，n = 29）、H-PEEK（氢等离子体处理，n = 38）、O-PEEK（氧等离子体处理，n = 38）、H/O-PEEK（气体混合比为 2:1 的氢/氧等离子体处理，n = 38）。然后，检查每组试件的表面粗糙度、表面接触角、表面结晶度、表面显微硬度和人成骨细胞覆盖面积。
与未处理组相比，等离子体处理组的亲水性、结晶度和显微硬度显著增加，而在 0.02N 测试力以下，所有组的显微硬度测试结果均有显著差异。处理过的 PEEK 表面的细胞密度明显高于未处理的 PEEK 表面。氧和 H/O 等离子体处理最为有效，而 H/O 等离子体处理达到相同效果的速度比 H 等离子体处理快十倍。
氢-氧、2/1 混合等离子体处理结合了氢等离子体和氧等离子体的效果，可显著改善 PEEK 植入材料的表面性能，如亲水性、结晶度、表面显微硬度和 HOB 细胞黏附性。
