Cerpa Manito Santiago, Sánchez Trancón Angel, Torrado Sierra Oscar, Baptista António M G, Serra Pedro Miguel
Ophthalmology Clinic Vista Sánchez Trancón, Badajoz, Spain.
Centre of Physics, University of Minho, Braga, Portugal.
Clin Ophthalmol. 2020 Oct 29;14:3563-3573. doi: 10.2147/OPTH.S258817. eCollection 2020.
The distance between an implantable collamer lens (ICL) and the crystalline lens, namely vault, is a space regulated by the interaction of the ICL and the anatomical structures of the eye. This study analysed the differences in vault size between fellow eyes with similar anterior segment biometry.
A retrospective case series analysed 109 cases of patients bilaterally implanted with EVO-V4c. Patients were analysed pre- and postoperatively using anterior segment optical coherence tomography. The range of vault inter-eye differences was defined as the 95% confidence interval of the differences. Bivariate correlation was applied to seek for associations between vault inter-eye differences with biometric and lens parameters (angle-to-angle, anterior chamber depth, crystalline lens rise, central corneal thickness, central keratometry, ICL spherical equivalent, horizontal compression, postoperative pupil diameter and vault).
Mean vault inter-eye differences were similar between fellow eyes (26.0 ± 122.5 µm). The 95% confidence interval range of the differences was ±240.1 µm, nearly 50% of the cases presented vault inter-eye differences higher than 100 µm. The vault of the first operated eye explained 81% of the variance in the second eye vault. Vault inter-eye differences were positively correlated with the level of horizontal compression and with vault magnitude.
Vaults measured in fellow eyes may present considerable differences, which can reach 25% of the common vault range. This reflects some degree of baseline variability in the vault. Clinically, these differences assume special relevance in cases where low or high vaults are expected.
可植入式胶原晶状体（ICL）与晶状体之间的距离，即房角，是由ICL与眼睛解剖结构相互作用所调节的空间。本研究分析了具有相似眼前节生物测量值的双眼之间房角大小的差异。
一项回顾性病例系列研究分析了109例双侧植入EVO-V4c的患者。使用眼前节光学相干断层扫描对患者进行术前和术后分析。房角眼间差异的范围定义为差异的95%置信区间。应用双变量相关性分析来寻找房角眼间差异与生物测量和晶状体参数（角对角、前房深度、晶状体升高、中央角膜厚度、中央角膜曲率、ICL球镜等效度、水平压缩、术后瞳孔直径和房角）之间的关联。
双眼之间的平均房角眼间差异相似（26.0±122.5μm）。差异的95%置信区间范围为±240.1μm，近50%的病例房角眼间差异高于100μm。第一只手术眼的房角解释了第二只眼房角81%的方差。房角眼间差异与水平压缩程度和房角大小呈正相关。
在双眼测量的房角可能存在相当大的差异，可达共同房角范围的25%。这反映了房角存在一定程度的基线变异性。临床上，这些差异在预期低房角或高房角的情况下具有特殊意义。
