Zhang Xi-Fang, Li Meng, Shi Yan, Wan Xiu-Hua, Wang Huai-Zhou
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Ophthalmology, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing 100730, China.
Int J Ophthalmol. 2020 Apr 18;13(4):625-631. doi: 10.18240/ijo.2020.04.15. eCollection 2020.
To evaluate the intra-operator repeatability of time domain and swept-source Fourier domain anterior segment optical coherence tomography (AS-OCT), namely, Visante AS-OCT and Casia SS-1000 OCT, in measuring the preoperative parameters of implantable collamer lens (ICL) in myopic eyes, as well as the agreement between the two devices.
A total of 97 eyes from 49 myopes were investigated in this prospective case series study. The anterior chamber depth (ACD), angle-to-angle distance (ATA), pupil diameter (PD) and crystalline lens rise (CLR) in all subjects were measured for three times during one session by the same operator. The repeatability was evaluated using the within-subject standard deviation (Sw), repeatability limits and intraclass correlation coefficients (ICC). The agreement between the two systems was evaluated using the Bland-Altman plots and 95% limits of agreement (LoA).
The repeatability limits of Visante AS-OCT in measuring ACD, ATA, PD and CLR were 0.099, 0.141, 0.304, and 0.079 mm, respectively. The repeatability limits of Casia SS-1000 OCT in measuring ACD, ATA, PD, and CLR were 0.105, 0.127, 0.357, and 0.082 mm, respectively. Excellent repeatability could be attained in both devices, with the ICC>0.8 for all the measured variables. The interdevice agreement was excellent (>0.05) for ACD and ATA, but poor (<0.05) for PD and CLR.
Good repeatability can be attained by time domain and swept-source Fourier-domain OCT for all the measured variables. Moreover, interdevice agreement analysis suggests that interchangeable measurements between two devices can be achieved for ACD and ATA, but not for PD and CLR; but the differences in measurements were not clinically significant.
评估时域和扫频源傅里叶域眼前节光学相干断层扫描（AS - OCT），即Visante AS - OCT和Casia SS - 1000 OCT，在测量近视眼可植入式角膜接触镜（ICL）术前参数时的操作者内重复性，以及这两种设备之间的一致性。
在这项前瞻性病例系列研究中，共对49例近视患者的97只眼进行了研究。同一名操作者在一次检查过程中对所有受试者的前房深度（ACD）、角间距（ATA）、瞳孔直径（PD）和晶状体抬高（CLR）进行三次测量。使用受试者内标准差（Sw）、重复性限和组内相关系数（ICC）评估重复性。使用Bland - Altman图和95%一致性界限（LoA）评估两种系统之间的一致性。
Visante AS - OCT测量ACD、ATA、PD和CLR的重复性限分别为0.099、0.141、0.304和0.079 mm。Casia SS - 1000 OCT测量ACD、ATA、PD和CLR的重复性限分别为0.105、0.127、0.357和0.082 mm。两种设备均可获得出色的重复性，所有测量变量的ICC>0.8。两种设备之间对于ACD和ATA的一致性良好（>0.05），但对于PD和CLR则较差（<0.05）。
时域和扫频源傅里叶域OCT对于所有测量变量均可获得良好的重复性。此外，设备间一致性分析表明，两种设备对于ACD和ATA可进行互换测量，但对于PD和CLR则不行；不过测量差异在临床上无显著意义。
