Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Metabolic Disorders Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
BMC Med Inform Decis Mak. 2020 Nov 10;20(1):291. doi: 10.1186/s12911-020-01312-w.
Akkermansia muciniphila is an anaerobic bacterium residing in the healthy intestinal tract of host and its quantity has a negative correlation with various host diseases. This study for the first time provides a holistic bibliometric aspect of Akkermansi muciniphila research in the literature and shows the hot topic terms of these articles in any period of time.
Scopus database was selected to retrieve documents relevant to Akkermansia muciniphila in any language up to 2019. The bibliometric profile of Akkermansia muciniphila articles including subject area, year distribution, citations, institutions, journals, authors, and countries was systematically characterized and the collaboration networks of authors and countries as well as the burst detection algorithm of the words in the titles, abstracts and keywords were visualized.
There is a progressive growing trend in research on Akkermansia from 2004 to 2019 with a total of 566 articles during this period. Out of 353 original articles, there are 194 animal studies (155 studies on mice) and 112 human studies. Also, 65 various diseases were investigated in these studies. The most focused conditions are obesity (71 articles) and type2 diabetes (39 articles). The United States is the leading country on Akkermansia publications (n = 132), followed by China (n = 95). Frontiers in Microbiology is the most dominant journal with 23 Akkermansia publications. In addition, "cancer" is the hot topic of recent Akkermansia research.
Akkermansia research is of progressive interest during the last decade and the studies on this subject move towards its relationship with cancer and its promising effect on health.
阿克曼氏菌（Akkermansia muciniphila）是一种厌氧细菌，存在于宿主健康的肠道中，其数量与各种宿主疾病呈负相关。本研究首次提供了阿克曼氏菌研究文献的整体计量学方面的信息，并展示了这些文章在任何时间段的热门主题术语。
选择 Scopus 数据库，以任何语言检索截至 2019 年与阿克曼氏菌相关的文献。系统地描述阿克曼氏菌文章的计量学概况，包括主题领域、年份分布、引用、机构、期刊、作者和国家，并可视化作者和国家的合作网络以及标题、摘要和关键词中单词的突发检测算法。
从 2004 年到 2019 年，对阿克曼氏菌的研究呈渐进式增长趋势，在此期间共有 566 篇文章。在 353 篇原始文章中，有 194 篇动物研究（155 篇关于老鼠的研究）和 112 篇人类研究。此外，这些研究还调查了 65 种不同的疾病。最受关注的疾病是肥胖症（71 篇文章）和 2 型糖尿病（39 篇文章）。美国是阿克曼氏菌出版物的领先国家（n=132），其次是中国（n=95）。微生物学前沿杂志是发表阿克曼氏菌文章最多的期刊，有 23 篇。此外，“癌症”是最近阿克曼氏菌研究的热门话题。
在过去十年中，阿克曼氏菌的研究兴趣不断增加，关于阿克曼氏菌的研究正朝着其与癌症的关系及其对健康的潜在影响方向发展。
