Department of Dermatovenerology and Cosmetology, NJSC "Semey Medical University", Semey, Republic of Kazakhstan.
Nazarbayev University School of Medicine, Nur-Sultan, Republic of Kazakhstan.
PLoS One. 2020 Nov 10;15(11):e0241445. doi: 10.1371/journal.pone.0241445. eCollection 2020.
Vitiligo is an acquired depigmenting skin disease which is often accompanied by mental distress. There are numerous studies dedicated to local and global prevalence of depression in patients with vitiligo but anxiety has not been recognized as a major mental problem within named population. We aimed to evaluate the prevalence of anxiety among patients with vitiligo from different countries and to compare it with patients suffering from eczema, psoriasis, and acne.
In November 2019, we conducted a systematic search for observational studies that examined the prevalence of anxiety in vitiligo patients. Fifteen studies comprising 1176 patients with vitiligo were included to our systematic review.
The general prevalence of anxiety among vitiligo patients was equal to 35.8%. Statistically significant difference in anxiety rates was found among female and male patients (47.32% vs 42.4%) (P = 0.03), but the clinical relevance of this issue remains arguable. In addition, the pooled odds ratio among vitiligo and non-vitiligo patients did not indicate a statistical significance among patients coming from different continents.
The pooled prevalence of anxiety among vitiligo patients worldwide was comparable to other severe skin disorders. This finding accentuates the necessity of anxiety awareness in management of patients with skin diseases.
白癜风是一种获得性皮肤色素脱失病，常伴有精神困扰。有许多研究致力于探讨白癜风患者中抑郁的局部和全球患病率，但焦虑尚未被认为是该人群中的主要精神问题。我们旨在评估来自不同国家的白癜风患者中焦虑的患病率，并将其与湿疹、银屑病和痤疮患者进行比较。
我们于 2019 年 11 月进行了一项系统搜索，以寻找评估白癜风患者焦虑患病率的观察性研究。共有 15 项研究纳入了 1176 名白癜风患者，进行了系统综述。
白癜风患者的总体焦虑患病率为 35.8%。在女性和男性患者中，焦虑发生率存在统计学显著差异（47.32%比 42.4%）（P=0.03），但这一问题的临床相关性仍存在争议。此外，来自不同大洲的患者中，白癜风患者与非白癜风患者的汇总优势比没有统计学意义。
全球白癜风患者的焦虑患病率与其他严重皮肤疾病相当。这一发现强调了在皮肤病患者管理中关注焦虑问题的必要性。
