Gouagna Louis Clément, Damiens David, Oliva Clélia F, Boyer Sébastien, Le Goff Gilbert, Brengues Cécile, Dehecq Jean-Sébastien, Raude Jocelyn, Simard Frédéric, Fontenille Didier
MIVEGEC, IRD, CNRS, Université Montpellier, CEDEX 5, 34394 Montpellier, France.
Medical and Veterinary Entomology Unit, Institut Pasteur du Cambodge, Phnom Penh 12201, Cambodia.
Insects. 2020 Nov 7;11(11):770. doi: 10.3390/insects11110770.
The global expansion of together with the absence of specific treatment and vaccines for most of the arboviruses it transmits, has stimulated the development of more sustainable and ecologically acceptable methods for control of disease transmission through the suppression of natural vector populations. The sterile insect technique (SIT) is rapidly evolving as an additional tool for mosquito control, offering an efficient and more environment-friendly alternative to the use of insecticides. Following the devastating chikungunya outbreak, which affected 38% of the population on Reunion Island (a French overseas territory in the southwest of the Indian Ocean), there has been strong interest and political will to develop effective alternatives to the existing vector control strategies. Over the past 10 years, the French Research and Development Institute (IRD) has established an SIT feasibility program against on Reunion Island in collaboration with national and international partners. This program aimed to determine whether the SIT based on the release of radiation-sterilized males is scientifically and technically feasible, and socially acceptable as part of a control strategy targeting the local population. This paper provides a review of a multi-year and a particularly broad scoping process of establishing the scientific and technological feasibility of the SIT against on Reunion Island. It also draws attention to some prerequisites of the decision-making process, through awareness campaigns to enhance public understanding and support, social adoption, and regulatory validation of the SIT pilot tests.
由于其传播的大多数虫媒病毒缺乏特异性治疗方法和疫苗，其在全球范围内的传播促使人们开发更可持续且生态上可接受的方法，通过抑制自然媒介种群来控制疾病传播。昆虫不育技术（SIT）正迅速发展成为蚊虫控制的一种补充工具，为使用杀虫剂提供了一种高效且更环保的替代方法。在留尼汪岛（印度洋西南部的一个法国海外领地）爆发毁灭性的基孔肯雅热疫情，影响了38%的人口之后，人们对开发现有媒介控制策略的有效替代方法产生了浓厚兴趣并形成了政治意愿。在过去10年里，法国研发机构（IRD）与国家和国际伙伴合作，在留尼汪岛建立了一项针对[蚊虫名称未给出]的昆虫不育技术可行性计划。该计划旨在确定基于释放经辐射绝育雄蚊的昆虫不育技术在科学技术上是否可行，以及作为针对当地[蚊虫名称未给出]种群的控制策略的一部分在社会上是否可接受。本文回顾了在留尼汪岛建立针对[蚊虫名称未给出]的昆虫不育技术的科学技术可行性的多年且特别广泛的范围界定过程。它还通过提高公众理解和支持的宣传活动、社会采用以及昆虫不育技术试点测试的监管验证，提请人们注意决策过程的一些先决条件。
