An Artificial Intelligence Approach to the Assessment of Abnormal Lid Position.

New artificial intelligence (AI) approaches to facial analysis show promise in the clinical evaluation of abnormal lid position. This could allow more naturalistic, quantitative, and automated assessment of lid position. The aim of this article was to determine whether OpenFace, an AI approach to real-time facial landmarking and analysis, can extract clinically useful measurements from images of patients before and after ptosis correction. Manual and AI-automated approaches to vertical palpebral aperture measurement of 128 eyes in pre- and postoperative full-face images of ptosis patients were compared in this study. Agreement in interpupillary distance to vertical palpebral aperture ratio between clinicians and an AI-based system was assessed. Image quality varied highly with interpupillary distance defined by a mean of 143.4 pixels (min = 60, max = 328, SD = 80.3 pixels). A Bland-Altman analysis suggests a good agreement between manual and AI analysis of vertical palpebral aperture (94.4% of measurements falling within 2 SDs of the mean). Correlation between the 2 methods yielded a Pearson's r(126) = 0.87 ( < 0.01) and r = 0.76. This feasibility study suggests that existing, open-source approaches to facial analysis can be applied to the clinical assessment of patients with abnormal lid position. The approach could be extended to further quantify clinical assessment of oculoplastic conditions.