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富血小板血浆在美容和医学皮肤科应用中的进展

Progress in the Use of Platelet-rich Plasma in Aesthetic and Medical Dermatology.

作者信息

Lin Mao-Ying, Lin Chrang-Shi, Hu Sindy, Chung Wen-Hung

机构信息

Dr. MY Lin is with the Department of Dermatology at Xiamen Chang Gung Hospital in Xiamen, Fujian, China.

Dr. CS Lin is with National Yang-Ming University and Dr. Lin Skin Clinic in Taipei, Taiwan.

出版信息

J Clin Aesthet Dermatol. 2020 Aug;13(8):28-35. Epub 2020 Aug 1.

PMID:33178379
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7595356/
Abstract

Platelet-rich plasma (PRP) has been receiving considerable attention in the field of dermatology since the elucidation of its mechanism and reports of its clinical efficacy. PRP alone or in combination with other therapies has demonstrated benefits for some cosmetic problems and skin diseases. Only a few transient or short-term side effects have been reported with the use of PRP. In this review, we highlight the potential efficacy and benefits of PRP with a focus on its applications in skin rejuvenation, androgenic alopecia, alopecia areata, chronic vitiligo, melasma, inflammatory nail disorders, and psoriasis. We suggest that detailed studies be conducted to standardize PRP preparation and optimize treatment methods in order to further improve its usefulness.

摘要

自从血小板富集血浆(PRP)的作用机制被阐明以及其临床疗效的报告出现以来,它在皮肤科领域一直备受关注。单独使用PRP或与其他疗法联合使用已显示出对一些美容问题和皮肤疾病有益。使用PRP仅报告了少数短暂或短期的副作用。在本综述中,我们重点介绍PRP在皮肤年轻化、雄激素性脱发、斑秃、慢性白癜风、黄褐斑、炎症性甲病和银屑病中的应用,突出其潜在疗效和益处。我们建议进行详细研究以规范PRP的制备并优化治疗方法,从而进一步提高其效用。

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本文引用的文献

1
[Vitiligo and Koebner phenomenon following platelet-rich plasma injections].[富血小板血浆注射后出现白癜风及同形反应]
Pan Afr Med J. 2019 Feb 4;32:58. doi: 10.11604/pamj.2019.32.58.16779. eCollection 2019.
2
Platelet-Rich Plasma and Its Utilities in Alopecia: A Systematic Review.富血小板血浆及其在脱发中的应用:系统评价。
Dermatol Surg. 2020 Jan;46(1):93-102. doi: 10.1097/DSS.0000000000001965.
3
Evaluation of platelet-rich plasma vs intralesional steroid in treatment of alopecia areata.富血小板血浆与病灶内注射类固醇治疗斑秃的疗效评估。
J Cosmet Dermatol. 2019 Oct;18(5):1456-1462. doi: 10.1111/jocd.12858. Epub 2019 May 10.
4
Fluid platelet-rich fibrin stimulates greater dermal skin fibroblast cell migration, proliferation, and collagen synthesis when compared to platelet-rich plasma.与富血小板血浆相比,富含血小板的纤维蛋白凝胶可刺激真皮皮肤成纤维细胞的迁移、增殖和胶原合成。
J Cosmet Dermatol. 2019 Dec;18(6):2004-2010. doi: 10.1111/jocd.12955. Epub 2019 Apr 16.
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Intramatricial platelet-rich plasma therapy: A novel treatment modality in refractory nail disorders.基质内富血小板血浆疗法:难治性甲病的一种新治疗方法。
Dermatol Ther. 2019 Mar;32(2):e12831. doi: 10.1111/dth.12831. Epub 2019 Feb 18.
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Platelet-rich plasma versus combined fractional carbon dioxide laser with platelet-rich plasma in the treatment of vitiligo: a comparative study.富血小板血浆与二氧化碳点阵激光联合富血小板血浆治疗白癜风的对比研究
Clin Cosmet Investig Dermatol. 2018 Nov 8;11:551-559. doi: 10.2147/CCID.S178817. eCollection 2018.
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Use of platelet-rich plasma to suspend noncultured epidermal cell suspension improves repigmentation after autologous transplantation in stable vitiligo: a double-blind randomized controlled trial.应用富含血小板的血浆悬浮非培养表皮细胞悬液提高稳定期白癜风自体移植后复色效果:一项双盲随机对照试验。
Int J Dermatol. 2019 Apr;58(4):472-476. doi: 10.1111/ijd.14286. Epub 2018 Dec 2.
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Effect of Platelet-Rich Plasma Injection for Rejuvenation of Photoaged Facial Skin: A Randomized Clinical Trial.富血小板血浆注射对面部光老化皮肤年轻化的效果:一项随机临床试验。
JAMA Dermatol. 2018 Dec 1;154(12):1447-1452. doi: 10.1001/jamadermatol.2018.3977.
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Autologous pure platelet-rich plasma injections for facial skin rejuvenation: Biometric instrumental evaluations and patient-reported outcomes to support antiaging effects.自体富血小板血浆注射用于面部皮肤年轻化:支持抗衰老效果的生物计量仪器评估和患者报告结果。
J Cosmet Dermatol. 2019 Aug;18(4):985-995. doi: 10.1111/jocd.12802. Epub 2018 Oct 23.
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Laser Ablation of the Recipient Area With Platelet-Rich Plasma-Enriched Epidermal Suspension Transplant in Vitiligo Surgery: A Pilot Study.白癜风手术中富血小板血浆强化表皮悬浮移植对受区的激光消融:一项初步研究。
Dermatol Surg. 2019 Jan;45(1):83-89. doi: 10.1097/DSS.0000000000001641.