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支气管哮喘患者生活质量评估

Assessment of Quality of Life in Bronchial Asthma Patients.

作者信息

Ali Rashid, Ahmed Naseem, Salman Muhammad, Daudpota Sofia, Masroor Madiha, Nasir Muhammad

机构信息

Chest Medicine, Jinnah Postgraduate Medical Centre, Karachi, PAK.

Paediatrics and Child Health, The Aga Khan University, Karachi, PAK.

出版信息

Cureus. 2020 Oct 8;12(10):e10845. doi: 10.7759/cureus.10845.

Abstract

Introduction Asthma, a well-known chronic respiratory disease, is common worldwide. This study aimed to assess the quality of life in bronchial asthma patients and to determine the factors leading to poor quality of life among these patients. Materials and methods A cross-sectional study was conducted at a public sector hospital. The sample size was calculated as 134, with a nonprobability consecutive sampling technique. The Ethical Review Committee approved the study protocol. Demographic and asthma quality of life data were collected via a questionnaire. Data were analyzed IBM SPSS Statistics for Windows, Version 19.0 (Armonk, NY: IBM Corp.). Multivariate logistic regression was performed to observed the effect of these variables on the poor quality of life. A regression coefficient and odds ratio with a confidence interval of 95% and P-value ≤ .05 were taken as significant. Results The average age of patients was 40.6 ± 9.5 years. In this study, 96 of 134 patients (71.4%) with bronchial asthma reported a poor quality of life. In the univariate analysis, advanced age (≥ 40 years), obesity, being female, family history of asthma, pets at home, and moderate severity of asthma significantly contributed to poor quality of life. Multivariate logistic regression was performed, and it was observed that advanced age (≥ 40 years), being female, a pet at home, and moderate severity of asthma were four to 13 times more likely to predict a poor quality of life for patients with bronchial asthma. Conclusions The severity of asthma significantly contributed to poor quality of life. Health facilitators should look into the causes of such risk to increase the perception of health-related quality of life (HRQoL) among asthma patients.

摘要

引言 哮喘是一种广为人知的慢性呼吸道疾病,在全球范围内都很常见。本研究旨在评估支气管哮喘患者的生活质量,并确定导致这些患者生活质量差的因素。

材料与方法 在一家公立医院进行了一项横断面研究。采用非概率连续抽样技术,样本量计算为134例。伦理审查委员会批准了研究方案。通过问卷调查收集人口统计学和哮喘生活质量数据。使用IBM SPSS Statistics for Windows 19.0版(纽约州阿蒙克:IBM公司)对数据进行分析。进行多因素逻辑回归以观察这些变量对生活质量差的影响。将回归系数、95%置信区间的比值比和P值≤0.05视为具有统计学意义。

结果 患者的平均年龄为40.6±9.5岁。在本研究中,134例支气管哮喘患者中有96例(71.4%)报告生活质量差。在单因素分析中,高龄(≥40岁)、肥胖、女性、哮喘家族史、家中养宠物以及哮喘中度严重程度显著导致生活质量差。进行了多因素逻辑回归分析,结果显示高龄(≥40岁)、女性、家中养宠物以及哮喘中度严重程度使支气管哮喘患者生活质量差的预测可能性增加4至13倍。

结论 哮喘的严重程度显著导致生活质量差。健康促进者应探究此类风险的原因,以提高哮喘患者对健康相关生活质量(HRQoL)的认知。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4331/7651774/f38548143660/cureus-0012-00000010845-i01.jpg

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